Live birth in a 50-year-old woman following in vitro fertilization-embryo transfer with autologous oocytes: a rare case report.

Objective: To report a live birth with in vitro fertilization (IVF) from a 50-year-old woman with homologous oocytes.

Design: Case report.

Setting: Referral center.

Congenital malformations among babies born following letrozole or clomiphene for infertility treatment.

Context: Clomiphene citrate (CC) is the first line drug for ovulation induction but because of its peripheral antiestrogenic effect, letrozole was introduced as the 2nd line drug. It lacks the peripheral antiestrogenic effect and is associated with similar or even higher pregnancy rates. Since letrozole is a drug for breast cancer, its use for the purpose of ovulation induction became controversial in the light of studies indicating an increased incidence of congenital malformations.

Assessment of sub-endometrial blood flow parameters following dydrogesterone and micronized vaginal progesterone administration in women with idiopathic recurrent miscarriage: a pilot study.

Aim: To evaluate differences in uteroplacental blood flow and pregnancy outcome in women with idiopathic recurrent spontaneous miscarriage (IRSM) following administration of micronized vaginal progesterone and oral dydrogesterone.

Methods: One hundred and thirty-three women (aged 23-40 years) who had had early miscarriages and spontaneous conception participated. Oral dydrogesterone (group A, n = 51) and micronized vaginal progesterone (group B, n = 50) were administrated for luteal support and compared.

Endometrial receptivity markers in infertile women stimulated with letrozole compared with clomiphene citrate and natural cycles.

Though various advantages associated with the use of letrozole as an ovulation inducing drug are documented, there is inadequate information regarding its effect on endometrial receptivity. Expression of endometrial receptivity markers including αvβ3 integrin, L-selectin, LIF, and pinopods during the implantation window in infertile women stimulated with letrozole or clomiphene citrate (CC), and spontaneous cycles is investigated. A total of 36 women were included in the study out of which 16 women were diagnosed with primary unexplained infertility and the other 20 women with severe oligoasthenozoospermic/azoospermic male partners.

Recurrent implantation success in consecutive embryo transfer cycles: a unique case report.

We describe here a unique case of a woman with an azoospermic male partner conceiving each time during ten consecutive in-vitro fertilization embryo transfer (IVF-ET) cycles. A 27 year old woman reported with primary infertility to our out-patient department at the Institute of Reproductive Medicine, Salt Lake, India in November 2001. Ten consecutive IVF-ET cycles including both, fresh and frozen embryos were performed over a span of ten years.

Comparison of oral dydrogestrone with progesterone gel and micronized progesterone for luteal support in 1,373 women undergoing in vitro fertilization: a randomized clinical study.

Objective: To compare the efficacy of oral dydrogesterone with that of micronized vaginal P gel and micronized P capsule for luteal supplementation.

Design: Prospective, randomized clinical study.

Setting: Institute of Reproductive Medicine, Kolkata, India.

Analysis of spindle characteristics and embryo quality in mice stimulated with letrozole using Polscope imaging.

Objective: To explore the effect of letrozole as an ovulation inducing agent on oocyte and embryo quality in mice model.

Design: Prospective study.

Setting: Institute of Reproductive Medicine, Kolkata, India.

Comparison of letrozole with continuous gonadotropins and clomiphene-gonadotropin combination for ovulation induction in 1387 PCOS women after clomiphene citrate failure: a randomized prospective clinical trial.

Purpose: Letrozole, though reported to be an effective ovulation inducing agent, warrants larger randomized trials. The purpose of this study is to compare the efficacy of letrozole with that of rFSH and clomiphene citrate(CC)/rFSH for ovarian stimulation in IUI cycles.

Methods: Randomized, prospective, single-blinded clinical trial.

Luteal phase estradiol level: a potential predictive marker for successful pregnancy in in vitro fertilization/intracytoplasmic sperm injection.

Objective: To analyze the role of luteal E(2), P, and FSH levels in the prediction of clinical pregnancy in stimulated cycles.

Design: Prospective study.

Setting: Institute of Reproductive Medicine, Salt Lake, Kolkata, India.

Surgical correction of rare Müllerian anomalies and spontaneous pregnancies: a case report.

Objective: To surgically reconstruct rare Müllerian duct anomalies with varying degrees of bladder exstrophy and congenital absence of ampullary portion of fallopian tube.

Design: Case report.

Setting: Institute of Reproductive Medicine, Salt Lake, Kolkata, India.

Role of latent genital tuberculosis in repeated IVF failure in the Indian clinical setting.

Genital tuberculosis is reported to be a major pelvic factor causing infertility in Indian women and often exists without any apparent signs and symptoms. The role of latent tuberculosis in repeated IVF failure in unexplained infertility is examined. 81 women with unexplained infertility having repeated IVF failure tested for Mycobacterium tuberculosis using PCR, ZN staining and BACTEC-460 culture were selected.