Publications by authors named "Asha Tadepalli"
Kyrieleis plaques: recognising a rare presentation of ocular inflammation.
Clin Exp Optom
November 2024
Article Synopsis
- Kyrieleis plaques are segmented inflammatory deposits found along retinal arteries, mostly appearing unilateral and near areas of retinal infection or inflammation.
- These plaques are located within vessel walls, not in the lumen or surrounding tissues, and are often referred to as segmental retinal periarteritis.
- Diagnosis of Kyrieleis plaques is determined by exclusion, as they must be differentiated from other retinal vessel issues like emboli and artery sheathing, which may require prompt medical attention.
Macrophages are crucial drivers of inflammatory corneal neovascularization and thus are potential targets for immunomodulatory therapies. We hypothesized that therapeutic use of cornea-derived mesenchymal stromal cells (cMSCs) may alter the function of macrophages. We found that cMSCs can modulate the phenotype and angiogenic function of macrophages.
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