Analysis of Online and Offline Head and Neck Image-guided Radiation Therapy.

Purpose: The introduction of a daily image-guided radiation therapy (IGRT) program is an important step. It has implications for the radiation therapy team in terms of accuracy, workflow, and decision making. This study assesses how successful a radiation therapy department has been in using this technology and the accuracy of individual decision making when comparing online and offline image match data.

Prostate radiotherapy clinical trial quality assurance: how real should real time review be? (A TROG-OCOG Intergroup Project).

Background And Purpose: Review of plans early in treatment offers the potential to reduce the chance of sub-optimal treatment delivery. We compare the use of real time reviews (RTR) either before randomization (pre-rand 3D RTR) or following randomization (post-rand 2D RTR).

Materials And Methods: PROFIT is an international randomised trial for men with prostate cancer which had credentialing via multiple dummy runs.

Defining a dose-response relationship for prostate external beam radiotherapy.

Introduction: We aimed to quantify a relationship between radiotherapy dose and freedom from biochemical failure (FFBF) in low- and intermediate-risk prostate cancer. To reduce confounding we used data with a standardised end-point, mature follow-up, low competing risk of metastatic failure, conventional fractionation and separate reporting for outcomes with hormonal therapy (HT).

Methods: A systematic review of the literature was carried out.