Publications by authors named "Asfold Parfenov"

Background: Anxiety and depression occur in a significant number of patients with inflammatory bowel diseases (IBD). The prevalence of anxiety and / or depression is 13-44.4% in patients with IBD compared to 4.

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Background: The objectives of the treatment of patients with ulcerative colitis (UC) in accordance with the STRIDE-I provision, involves endoscopic healing of the colon mucosa. Histological remission is associated with endoscopic healing, which can be a predictor of long-term results. Biological and cellular therapy is most effective in the early stages of the disease.

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Article Synopsis
  • FBD may be linked to reduced enzyme activity, particularly disaccharidases, which could improve diagnosis and treatment if identified early.
  • A study of 82 FBD patients found high rates of deficiencies in lactase (86.5%), maltase (48.7%), sucrase (50%), and glucoamylase (84.1%), with many showing reduced overall enzyme activity.
  • Results indicated that 95.2% of patients had low enzyme function related to carbohydrate digestion, suggesting a strong connection between disaccharidase deficiency and gastrointestinal symptoms in FBD.
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Successful colonization of the intestine requires that bacteria interact with the innate immune system and, in particular, neutrophils. Progression of inflammatory bowel diseases (IBD) is associated with alterations in gut microbiota, and dysbiosis in Crohn's disease (CD) patients is often associated with an expansion of Escherichia coli. Here, we investigated the ability of such E.

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One of the dysbioses often observed in Crohn's disease (CD) patients is an increased abundance of (10-100 fold compared to healthy individuals) (Gevers et al., 2014). The data reported is a large-scale proteome profile for isolates collected from CD patients and healthy individuals.

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