Publications by authors named "Asenbaum Ulrika"
Background: Ultra-low-dose CT (ULDCT) examinations of the chest at only twice the radiation dose of a chest X-ray (CXR) now offer a valuable imaging alternative to CXR. This trial prospectively compares ULDCT and CXR for the detection rate of diagnoses and their clinical relevance in a low-prevalence cohort of non-traumatic emergency department patients.
Methods: In this prospective crossover cohort trial, 294 non-traumatic emergency department patients with a clinically indicated CXR were included between May 2nd and November 26th of 2019 (www.
In this study, we assessed the prognostic relevance of temporal muscle thickness (TMT), likely reflecting patient's frailty, in patients with primary central nervous system lymphoma (PCNSL). In 128 newly diagnosed PCNSL patients TMT was analyzed on cranial magnetic resonance images. Predefined sex-specific TMT cutoff values were used to categorize the patient cohort.
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- The study explores the relationship between portal hypertension and sarcopenia in patients with advanced chronic liver disease, highlighting the need for systematic investigation of their combined effects on patient outcomes.
- Sarcopenia was found in 37.9% of the 203 participants, showing no correlation with measured portal hypertension levels, but was significantly linked to increased risk of hepatic decompensation and mortality.
- The findings indicate that sarcopenia is a critical independent risk factor for mortality in patients with advanced chronic liver disease regardless of the severity of portal hypertension.
Article Synopsis
- Perioperative stroke is a serious complication after CABG surgery, linked to atherosclerosis in the ascending aorta, which can lead to plaque detachment and embolization during the procedure.
- High-pitch computed tomography angiography (HP-CTA) is a non-invasive imaging method that helps detect and characterize these plaques in patients before CABG surgery.
- The study analyzed data from 719 patients and found a strong connection between the extent of atherosclerotic disease and perioperative stroke risk, with those having mixed plaques showing significantly higher stroke rates.
Purpose: We investigated the efficacy and analyzed the complication risk factors of peritoneovenous shunt in treating refractory chylous ascites following retroperitoneal lymph node dissection in patients with urological malignancies.
Materials And Methods: From April 2001 to March 2019 all patients with refractory chylous ascites after retroperitoneal lymph node dissection treated with peritoneovenous shunt were reviewed. Demographic characteristics, technical success, efficacy, patency period and complications were studied.
Temporal muscle thickness (TMT) was investigated as a novel surrogate marker on MRI examinations of the brain, to detect patients who may be at risk for sarcopenia. TMT was analyzed in a retrospective, normal collective cohort ( = 624), to establish standard reference values. These reference values were correlated with grip strength measurements and body mass index (BMI) in 422 healthy volunteers and validated in a prospective cohort ( = 130) of patients with various neurological disorders.
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- Low muscle mass is linked to increased health risks in patients with cirrhosis, and the skeletal-muscle index (SMI) is a common method for diagnosing muscle wasting, though it requires specialized technology to measure.
- A study analyzed cirrhotic patients' abdominal CT scans to compare multiple methods for evaluating muscle mass, including SMI, transversal psoas muscle thickness (TPMT), total psoas volume (TPV), and paraspinal muscle index (PSMI).
- The results showed that low muscle mass was common and linked to higher mortality risks, particularly with TPMT measurements, indicating that simpler methods could effectively assess muscle wasting in cirrhosis patients.
Article Synopsis
- The study investigates how normalized vascular intratumoral signal intensity values (nVITS) from pulsed arterial spin labeling (PASL) can help differentiate between meningiomas and dural metastases, which are often confused in standard MRI imaging.
- A total of 46 patients (30 with meningiomas and 16 with dural metastases) were analyzed, finding that meningiomas had significantly higher nVITS values compared to dural metastases.
- The research concluded that nVITS values are a quick, noninvasive MRI method that can accurately distinguish between these tumors based on their vascularity, with a 100% sensitivity and 81.2% specificity.
Objectives: To evaluate the influence of baseline parameters on the occurrence of stent-graft surface movement after endovascular aneurysm repair (EVAR) and to investigate its association with migration and stent-graft-related endoleaks (srEL).
Methods: In this retrospective, cross-sectional study, three-dimensional surface models of the stent-graft, delimited by landmarks using custom-built software, were derived from the pre-discharge and last follow-up computed tomography angiography (CTA). Stent-graft surface movement in the proximal anchoring zone between these examinations was considered significant at a threshold of 9 mm.
Postoperative liver dysfunction remains a major concern following hepatic resection. In order to identify patients who are at risk of developing liver dysfunction, indocyanine green (ICG) clearance has been proposed to predict postoperative liver function. All patients who underwent liver resection at the Medical University Vienna, Austria between 2006 and 2015 with preoperative ICG clearance testing (PDR, R15) were analyzed in this study.
View Article and Find Full Text PDFObjectives: To evaluate the influence of baseline clinical and morphological parameters on the occurrence of a late stent graft related endoleak (srEL; types 1 and 3) after endovascular aneurysm repair (EVAR).
Methods: This is a retrospective case control study of patients who were routinely followed up after EVAR of abdominal aortic aneurysms. Pre-interventional, pre-discharge, and last available multislice computed tomography angiogram (MSCTA) of 279 patients were analysed.
Background: Early diagnosis of acute compartment syndrome (ACS) of the leg is essential to improve the outcome. Direct invasive measurement is currently recommended to measure intracompartmental pressure. A non-invasive and reproducible means of making the diagnosis would be a step forward.
View Article and Find Full Text PDFObjectives: This study aimed to assess the correlation of temporal muscle thickness (TMT), measured on routine cranial magnetic resonance (MR) images, with lumbar skeletal muscles obtained on computed tomography (CT) images in brain metastasis patients to establish a new parameter estimating skeletal muscle mass on brain MR images.
Methods: We retrospectively analyzed the cross-sectional area (CSA) of skeletal muscles at the level of the third lumbar vertebra on computed tomography scans and correlated these values with TMT on MR images of the brain in two independent cohorts of 93 lung cancer and 61 melanoma patients (overall: 154 patients) with brain metastases.
Results: Pearson correlation revealed a strong association between mean TMT and CSA in lung cancer and melanoma patients with brain metastases (0.
Objectives: The purpose of this study was to evaluate the prognostic relevance of temporal muscle thickness (TMT) in melanoma patients with newly diagnosed brain metastases.
Methods: TMT was retrospectively assessed in 146 melanoma patients with newly diagnosed brain metastases on cranial magnetic resonance images. Chart review was used to retrieve clinical parameters, including disease-specific graded prognostic assessment (DS-GPA) and survival times.
Objectives: To compare the value of functional future liver remnant (functFLR) to established clinical and imaging variables in prediction of post-hepatectomy liver failure (PHLF) after major liver resection.
Methods: This retrospective, cross-sectional study included 62 patients, who underwent gadoxetic acid enhanced MRI and MDCT within 10 weeks prior to resection of ≥ 4 liver segments. Future liver remnant (FLR) was measured in MDCT using semi-automatic software.
Article Synopsis
- The study evaluated the effectiveness of standardized uptake values (SUV) and apparent diffusion coefficients (ADC) in assessing bone marrow involvement in lymphoma patients.
- Sixty patients with lymphoma underwent [F18]-FDG-PET/CT and whole-body diffusion-weighted imaging (WB-DWI) before routine bone marrow biopsies were performed.
- Results indicated that while SUVmax-ratios and ADCmean values could identify bone marrow involvement, the specificity for diffuse involvement was lower, highlighting the potential of [F18]-FDG-PET/CT and DWI in distinguishing affected areas from healthy bone marrow.
Article Synopsis
- The study examines how portal hypertension (PH) affects gadoxetic acid-enhanced liver MRI and its implications for diagnosis and prognosis.
- A retrospective analysis involved 178 patients with chronic liver disease, correlating results from MRI and hepatic venous pressure gradient (HVPG) measurements.
- Findings reveal that the presence of portal vein hyperintensity sign (PVHS) is a significant marker for severe PH and is associated with lower survival rates independent of other clinical scores.
Objectives: To evaluate the prognostic relevance of temporal muscle thickness (TMT) in brain metastasis patients.
Methods: We retrospectively analysed TMT on magnetic resonance (MR) images at diagnosis of brain metastasis in two independent cohorts of 188 breast cancer (BC) and 247 non-small cell lung cancer (NSCLC) patients (overall: 435 patients).
Results: Survival analysis using a Cox regression model showed a reduced risk of death by 19% with every additional millimetre of baseline TMT in the BC cohort and by 24% in the NSCLC cohort.
Article Synopsis
- The study investigated the effectiveness of various hybrid imaging methods for detecting bone marrow infiltration in lymphoma patients, specifically comparing [18F]-FDG-PET/CT, [18F]-FDG-PET/T1, and [18F]-FDG-PET/DWI.
- All three imaging combinations demonstrated similar sensitivity (81.3%), specificity (ranging from 95.5% to 97.7%), and accuracy (91.7% to 93.3%) for identifying bone marrow involvement, with no significant differences among them.
- Despite the [18F]-FDG-PET/T1 combination showing slightly better performance, the moderate sensitivity (62.5%) for detecting diffuse involvement indicated that bone marrow biopsy remains necessary for
Purpose: To define the diagnostic precision of non-specialized readers in the detection of type 2 endoleaks (T2EL) in arterial versus venous phase acquisitions, and to evaluate an approach for radiation dose reduction.
Methods: The pre-discharge and final follow-up multi-slice CT angiographies of 167 patients were retrospectively analyzed. Image data were separated into an arterial and a venous phase reading set.
Objectives: This prenatal MRI study evaluated the potential of diffusion tensor imaging (DTI) metrics to identify changes in the midbrain of fetuses with Chiari II malformations compared to fetuses with mild ventriculomegaly, hydrocephalus and normal CNS development.
Methods: Fractional anisotropy (FA) and apparent diffusion coefficient (ADC) were calculated from a region of interest (ROI) in the midbrain of 46 fetuses with normal CNS, 15 with Chiari II malformations, eight with hydrocephalus and 12 with mild ventriculomegaly. Fetuses with different diagnoses were compared group-wise after age-matching.
Objective: To assess a radiologist's detection rate of rib fractures in trauma CT when reading curved planar reformats (CPRs) of the ribs compared to reading standard MPRs.
Methods: Two hundred and twenty trauma CTs (146 males, 74 females) were retrospectively subjected to a software algorithm to generate CPRs of the ribs. Patients were split into two equal groups.
Article Synopsis
- This fetal MRI study focuses on identifying imaging parameters to distinguish between open neural tube defects (ONTDs) and closed neural tube defects (CNTDs) in fetuses with spina bifida.
- The study measured the clivus-supraocciput angle (CSA) and the maximum transverse diameter of the posterior fossa (TDPF) in three groups of fetuses: those with normal CNS, ONTDs, and CNTDs.
- Results showed that fetuses with ONTDs had a significantly smaller CSA than both normal controls and CNTDs, indicating that CSA could serve as a reliable imaging biomarker for differentiating between ONTDs and CNTDs during gestation.