Publications by authors named "Asel Aydeger"
Article Synopsis
- - Spinal cord injuries are prevalent globally and often result in permanent nerve function loss, prompting research into better treatment options and neural regeneration techniques.
- - The study focuses on developing specialized hybrid film scaffolds made from polycaprolactone (PCL) and poly-D,L-lactic-co-glycolic acid (PLGA), which are modified with specific peptides and nanoparticles to enhance motor neuron behavior and alignment.
- - Results reveal that scaffolds enhanced with gold nanoparticles significantly improve neuron orientation and regeneration capabilities, suggesting their potential effectiveness in treating spinal cord injuries in future applications.
In the field of neural tissue engineering, intensive efforts are being made to develop tissue scaffolds that can support an effective functional recovery and neural development by guiding damaged axons and neurites. Micro/nano-channeled conductive biomaterials are considered a promising approach for repairing the injured neural tissues. Many studies have demonstrated that the micro/nano-channels and aligned nanofibers could guide the neurites to extend along the direction of alignment.
View Article and Find Full Text PDFGold nanoparticles are emerging as promising nanomaterials to create nanoscale therapeutic delivery systems. The aim of the study was to synthesis of highly monodisperse and stable gold nanoparticles functionalized with polyethyleneimine (PEI) and polyethylene glycol (PEG), multiparametric investigation of their neuronal toxicological effects and evaluation of the cellular/suborgan biodistribution. Gold nanoparticles (AuNP and AuNP) were synthesized and their surfaces were electrostatically modified by PEI and PEG.
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