Publications by authors named "Asefa Shariq Ansari"
Article Synopsis
- The Omicron variant of SARS-CoV-2 includes various sublineages such as BA.2, BA.2.12.1, BA.4, and BA.5, which are now more prevalent than the earlier BA.1 variant.
- These sublineages have mutations that enhance binding to ACE2, reduce cell fusion capabilities, and significantly lower neutralizing antibody responses from previous infections or vaccines.
- However, booster shots using the original Wuhan-Hu-1 spike sequence can significantly enhance neutralizing antibody levels, suggesting that while initial vaccinations may be less effective against Omicron, boosters can still provide strong protection against severe illness.
