ZnO-nanorods Promoted Synthesis of α-amino Nitrile Benzofuran Derivatives using One-pot Multicomponent Reaction of Isocyanides.

Aims And Objective: In this work ZnO-nanorod (ZnO-NR) as reusable catalyst promoted Strecker-type reaction of 2,4-dihydroxyacetophenone, isopropenylacetylene, trimethylsilyl cyanide (TMSCN), primary amines and isocyanides at ambient temperature under solvent-free conditions and produced α-amino nitriles benzofuran derivatives in high yields. These synthesized compounds may have antioxidant ability.

Materials And Methods: ZnO-NRs in these reactions were prepared according to reported article.

Green Synthesis of 4H-pyran Derivatives Using Fe3O4-MNPs as Efficient Nanocatalyst: Study of Antioxidant Activity.

Aims And Objective: In this work, pyran derivatives were synthesized via a multicomponent reaction of ninhydrin, α-haloketones, dialkyl acetylenedicarboxylate, and triphenylphosphine in the presence of iron oxide magnetic nanoparticles (Fe3O4-MNPs) as efficient nanocatalyst in ethanol at room temperature.

Materials And Methods: The biosynthesis of Fe3O4-MNPs was performed by Clover Leaf water extract. In addition, antioxidant activity was examined for the prepared compounds employing DPPH radical scavenging and ferric reduction activity potential (FRAP) experiment and comparing results with synthetic antioxidants (TBHQ and BHT).