Publications by authors named "Ascension Hernando"
Article Synopsis
- The study investigates whether actively screening for pulmonary embolism (PE) can improve outcomes for patients hospitalized due to chronic obstructive pulmonary disease (COPD) exacerbations when compared to standard care.
- Conducted in Spain with 746 participants over several years, the trial compared the effects of an active PE diagnosis strategy (using D-dimer tests and CT scans) against usual care alone.
- Results showed no significant differences in key outcomes like readmission rates or deaths within 90 days between the two groups, indicating that the active search for PE may not offer additional benefits in this patient population.
Introduction: Some previous studies have suggested a high prevalence of pulmonary embolism (PE) during exacerbations of chronic obstructive pulmonary disease (ECOPD). The SLICE trial aims to assess the efficacy and safety of an active strategy for the diagnosis and treatment of PE (vs usual care) in patients hospitalized because of ECOPD.
Methods: SLICE is a phase III, prospective, international, multicenter, randomized, open-label, and parallel-group trial.