Autogenous bone with or without hydroxyapatite bone substitute augmentation in rat calvarium within a plastic cap.

Objectives: We evaluated the effect of autogenous bone (AB) and hydroxyapatite bone (HA) for the assessment of bone augmentation beyond the skeletal envelope in the rat calvarium.

Study Design: The calvaria of 12 rats were exposed and 2 plastic caps were placed with AB and HA or AB alone in the calvarium. Images of bone augmentation within the plastic caps were taken using micro-CT (R_mCT).

Micro-CT observation of angiogenesis in bone regeneration.

Objectives: Restoration of an adequate blood supply is essential for the bone healing process and is key to the success of bone augmentation procedures. In this study, we evaluated angiogenesis in rat calvarial flat bone defects using in vivo microfocus computed tomography (micro-CT).

Materials And Methods: Twenty rats were used.

In vivo bone regenerative effect of low-intensity pulsed ultrasound in rat calvarial defects.

Objectives: Low-intensity pulsed ultrasound (LIPUS) is a biophysical intervention in a bone repair process. However, neither the healing events of the flat bones of the skull using LIPUS nor the optimal stimulation settings are fully understood. The aim of this study was to evaluate the bone regenerative effect of LIPUS in rat calvarial flat bone defects by using in vivo microfocus computerized tomography (micro-CT).