Publications by authors named "Asami Magome"
Objectives: The production of expanded-spectrum beta-lactamases (ESBLs) and fluoroquinolone resistance in Enterobacteriaceae has become a global concern. The aim of this study was to investigate the spread of ESBL-producing and fluoroquinolone-resistant avian pathogenic Escherichia coli (APEC) in Kagoshima, a prefecture with the largest amount of poultry in Japan.
Methods: The antimicrobial susceptibility and genetic characteristics of 228 APEC strains isolated from 57 farms in Kagoshima Prefecture, Japan, between 2005 and 2017 were analysed.
Article Synopsis
- Pathogenic strains in swine lead to significant economic losses, particularly in Japan where antimicrobial use is higher compared to other farm animals.
- A recent study analyzed 1,708 strains from diseased swine over nearly three decades (1991-2019) and identified increasing multidrug-resistant strains, including resistant serogroups O116 and OSB9.
- The study found that although third-generation cephalosporins had a low resistance rate, alternative antimicrobials like apramycin and bicozamycin were more effective against highly multidrug-resistant strains.