Publications by authors named "Asami Abe"

Objective: The COVID-19 pandemic prompted the widespread adoption of telemedicine as an alternative to in-person care. This systematic scoping review evaluated the effectiveness, cost-efficiency, and challenges of telemedicine for patients with rheumatic diseases.

Methods: A comprehensive search of the MEDLINE database was conducted using specific terms related to rheumatoid or juvenile arthritis, and telemedicine.

View Article and Find Full Text PDF

Objective: To elucidate the therapeutic effect of orthopedic surgical intervention (OSI) in difficult-to-treat rheumatoid arthritis (D2T RA) compared with non-D2T RA.

Methods: A total of 534 recent surgeries were analyzed only in patients who had undergone OSI since 2016 and for whom a 12-month post-operative follow-up was available. D2T RA was determined according to the EULAR definition, and patients with D2T RA were matched to patients with non-D2T RA using propensity scores calculated by a logistic regression analysis.

View Article and Find Full Text PDF
Article Synopsis
  • The study compared the initial treatment responses of late-onset rheumatoid arthritis (LORA) patients aged 65 and older with those of young-onset rheumatoid arthritis (YORA) patients under 65, focusing on the influence of osteoarthritis (OA).
  • A retrospective analysis of RA patients referred to a clinic showed that LORA patients with significant OA experienced worse control over their disease and greater difficulties in daily activities after one year of treatment compared to those without OA.
  • In contrast, YORA patients did not show significant differences in daily activity limitations between those with and without OA, indicating that OA had a more pronounced effect on older RA patients.
View Article and Find Full Text PDF
Article Synopsis
  • * A majority of respondents indicated that over half of newly diagnosed patients were 65 or older, with a focus on achieving remission or low disease activity, while also prioritizing patient safety.
  • * Rheumatologists expressed concern about comorbidities and other factors that could interfere with optimal treatment, indicating a more complex management landscape for older patients with LORA.
View Article and Find Full Text PDF
Article Synopsis
  • Late-onset rheumatoid arthritis (LORA) is a type of arthritis that affects older people, and experts realized there wasn’t enough information on how to treat it.
  • A group of Japanese doctors discussed treatments, reviewed past studies, and worked together to make a set of recommendations for how to manage LORA effectively.
  • They found that one of the best treatments is methotrexate and that it's important to consider the health and daily lives of older patients when choosing the right treatment.
View Article and Find Full Text PDF
Article Synopsis
  • The study investigates how new antirheumatic drugs affect the characteristics of lymphoproliferative disorder (LPD) in rheumatoid arthritis (RA) patients, using data from 53 hospitals in Japan between 1999 and 2021.
  • A total of 752 patients with RA-associated LPD were compared to 770 with sporadic LPD, revealing notable differences in their clinical features and the impact of various drug combinations.
  • The findings suggest that medications taken before LPD onset may alter its characteristics, and recommend tocilizumab (TCZ) as a better treatment option after LPD has developed.
View Article and Find Full Text PDF

Background: In recent years, advances in pharmacotherapy for rheumatoid arthritis have dramatically improved the control of disease activity. However, a significant number of patients still develop hand deformity and require surgical reconstruction. The objective of this study was to evaluate the long-term efficacy and drawbacks of the Swanson metacarpophalangeal joint arthroplasty for patients with rheumatoid arthritis over 10 years.

View Article and Find Full Text PDF

Objective Sarcopenia is characterized by a loss of muscle mass and strength, which leads to frailty and mortality. Rheumatoid arthritis (RA) is considered to be a cause of sarcopenia. The present study assessed the effectiveness of biological disease-modifying antirheumatic drugs (bDMARDs) on sarcopenia.

View Article and Find Full Text PDF

Background: Although drug treatment strategies for rheumatoid arthritis (RA) are relatively well established, there is a paucity of evidence on the treatment in older patients. The purpose of this study is to build a registry for late-onset RA (LORA), which is expected to increase rapidly worldwide. In addition, we aim to propose optimal treatment strategies according to the patient background including frailty, thereby contributing to improving the quality of treatment and daily living in patients with RA.

View Article and Find Full Text PDF
Article Synopsis
  • Elderly patients with rheumatoid arthritis (RA) often face challenges using methotrexate (MTX) due to serious health issues, so the study investigated the safety and effectiveness of golimumab (GLM) as an alternative.
  • The findings showed that GLM had comparable survival rates (80.8% for elderly vs. 82.3% for younger patients) and improved disease activity scores in elderly patients over 52 weeks, regardless of their MTX treatment status.
  • Although GLM improved disease activity, it did not significantly impact the Health Assessment Questionnaire Disability Index (HAQ-DI), suggesting that while it’s effective, it may not enhance overall disability levels in elderly patients with RA.
View Article and Find Full Text PDF

Objectives: The incidence of femoral localized periosteal thickening (LPT), which can precede atypical femoral fracture (AFF), is not low (1-10%) in Japanese patients with autoimmune inflammatory rheumatic diseases (AIRDs). We explored the associations between underlying AIRDs and the prevalence of LPT.

Methods: We conducted post hoc analyses of two cohorts that included a total of 280 Japanese women, 105 of whom had AIRDs and had been taking bisphosphonate (BP) and prednisolone (PSL) and 175 of whom had rheumatoid arthritis (RA).

View Article and Find Full Text PDF

Background: In recent years, advances in pharmacotherapy for rheumatoid arthritis (RA) have dramatically improved the control of disease activity. However, a significant number of patients still develop forefoot deformity. The purpose of this study was to investigate the results of more than 20 years' follow-up of metatarsal neck shortening oblique osteotomy (SOO) for forefoot deformity in patients with RA.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to evaluate the effectiveness of the modified Thompson-Littler (m-TL) surgical method for correcting rheumatoid swan-neck deformity in patients with rheumatoid arthritis.
  • It involved 10 patients undergoing surgery on 27 fingers, with a follow-up period averaging 2.4 years, showing significant improvements in pain and pinch strength post-surgery.
  • Results indicated that while total range of motion decreased, patients experienced satisfactory aesthetic and functional improvements, especially in cases of less severe deformity.
View Article and Find Full Text PDF

The present study aims to evaluate changes in plantar pressure distribution after joint-preserving surgery for rheumatoid forefoot deformity. A retrospective study was performed on 26 feet of 23 patients with rheumatoid arthritis (RA) who underwent the following surgical combination: modified Mitchell's osteotomy (mMO) of the first metatarsal and shortening oblique osteotomy of the lateral four metatarsals. Plantar pressure distribution and clinical background parameters were evaluated preoperatively and one year postoperatively.

View Article and Find Full Text PDF

A 54-year-old woman suspected of having localised systemic sclerosis (SSc) started steroid treatment around 40 years old. She had Jaccoud's arthropathy in her right hand with severe deformities but no bone erosion. The metacarpophalangeal (MP) joint of the index through the little fingers was dislocated palmo-ulnarly with flexion contracture of about 120° and a swan-neck deformity.

View Article and Find Full Text PDF

Objective To evaluate the effectiveness and drug retention rate of golimumab (GLM) for long-term use in daily practice for patients with rheumatoid arthritis (RA). Methods Patients with RA who started GLM therapy with a minimum follow-up period of 52 weeks were included. The patients were divided into a biologic-naïve group and switch group.

View Article and Find Full Text PDF

Objective To investigate the clinical outcomes of rheumatoid arthritis (RA) patients who discontinued infliximab (IFX) treatment at our hospital. Methods Among 249 patients receiving IFX from 2007 to 2015, we retrospectively investigated the clinical courses of 18 who discontinued IFX after achieving the 28-joint disease activity score based on the erythrocyte sedimentation (DAS28-ESR) clinical remission (CR) and whose clinical courses were available continuously for 96 weeks after discontinuation. Results At IFX introduction, the median age was 56.

View Article and Find Full Text PDF

Objectives: This retrospective study aimed to investigate the risk factors associated with delayed wound healing (DWH) after orthopedic surgery in rheumatoid arthritis (RA) patients treated with biological disease-modifying antirheumatic drugs (bDMARDs).

Methods: We reviewed medical records of 276 orthopedic procedures for 187 RA patients treated with bDMARDs. As a preoperative nutritional status assessment, we evaluated body mass index, prognostic nutritional index (PNI), and controlling nutritional status (CONUT).

View Article and Find Full Text PDF

Hepcidin, a major regulator of iron metabolism and homeostasis, is regulated by inflammation. Recent studies have suggested that hepcidin and iron metabolism are involved in osteoporosis, and the aim of this study was to determine whether serum hepcidin levels are correlated with the degree of osteoporosis in patients with rheumatoid arthritis (RA). A total of 262 patients with RA (67.

View Article and Find Full Text PDF

Objectives: A pain-free stable wrist is a prerequisite for patients with rheumatoid arthritis to improve their activity of daily life. The present study investigated whether or not radiocarpal arthrodesis yielded good results for more than 20 years.

Methods: A retrospective study was performed on 20 unstable wrists in 17 patients with rheumatoid arthritis.

View Article and Find Full Text PDF

Objective: Digital joints affected by rheumatoid arthritis often have severe deformity and/or dislocation, and arthrodesis in a functional position is required.

Methods: Arthrodesis was performed using intraosseous wiring (modified Lister's method) from January 2011 to December 2015, and we investigated the union rate, postoperative complications, and patient satisfaction with the operation at the final follow-up. The DASH score, grip power, and pinch power were also investigated before the operation and at the final follow-up.

View Article and Find Full Text PDF

The objective of this retrospective study was to evaluate the outcomes of ulnar stump stabilization after ulna head resection using the FCU tendon by investigating the rate of postoperative extensor tendon rupture and click on forearm rotation. Wrist synovectomy (distal radioulnar joint (DRUJ), radiocarpal and midcarpal joints) and ulnar head resection combined with ulnar stump stabilizing procedure were performed in 58 wrists of 53 patients with RA in our hospital. Before operation, the dorsal subluxation ratio (DSR) of the ulnar head was measured with a multi-slice computed tomography (CT) images.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessionqbglprq4o05bgfq3r39q5403gr3uoqud): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once