When is Helicobacter pylori acquired in populations in developing countries? A birth-cohort study in Bangladeshi children.

Helicobacter pylori colonization is prevalent throughout the world, and is predominantly acquired during childhood. In developing countries, >70% of adult populations are colonized with H. pylori and >50% of children become colonized before the age of 10 years.

Rapid identification of and assessment of clarithromycin susceptibility from clinical specimens using FISH.

remains one of the most common bacterial infections worldwide. Clarithromycin resistance is the most important cause of eradication failures. Effective antibiotic therapies in infection must be rapidly adapted to local resistance patterns.

Role of cytokine polymorphisms in the risk of distal gastric cancer development.

We review the current information concerning the role of cytokine polymorphisms and the risk of develop distal gastric cancer in different populations. We have included populations colonized with Helicobacter pylori as well as populations without colonization. We found that the study of polymorphisms alone seems insufficient to assess gastric cancer risk and it is necessary to examine environmental factors in different ethnic groups and geographic areas along with the study of H.

Seroprevalence of Helicobacter pylori in New York City populations originating in East Asia.

Helicobacter pylori prevalence is higher in developing countries than in industrialized countries, and within the latter, higher among immigrants than among nativeborn residents. Using a point-prevalence survey, we sought to identify risk factors for H. pylori seropositivity in US urban East Asian-born populations.

Phenotypic and genotypic variation in methylases involved in type II restriction-modification systems in Helicobacter pylori.

To determine relationships between Helicobacter pylori geographical origin and type II methylase activity, we examined 122 strains from various locations around the world for methylase expression. Most geographic regions possessed at least one strain resistant to digestion by each of 14 restriction endonucleases studied. Across all of the strains studied, the average number of active methylases was 8.