A comparative study of human amniotic membrane, tilapia skin collagen, and Centella asiatica derived gel to treat burn wound in rat model.

In the quest for an ideal wound healing material, human amniotic membrane (AM), tilapia skin collagen (TSC), and Centella asiatica (CA) have been studied separately for their healing potential. In this study, we formulated AM, TSC, and CA gel and studied their competency and wound healing efficacy in vivo. Gel was formulated using AM, TSC, CA, Carbopol 934, acrylic acid, glycerine, and triethanolamine and physicochemical properties e.

Silver Nanoparticle Incorporated Human Amniotic Membrane Gel Accelerates Second-Degree Burn Wound Healing in Wister Rat.

Burn has terrible consequences for the affected patients, making them vulnerable to wound infections and septicemia, which results in physical and mental disability and death, necessitating superior treatment options. Human amniotic membrane (HAM) has been utilized in burn wounds for decades for its low immunogenicity, angiogenic, anti-inflammatory, and antimicrobial properties and for promoting epithelialization. Silver nanoparticles (AgNPs), on the other hand, have antimicrobial properties and promote fibroblast migration.

Photonic crystal nanostructure as a photodetector for NaCl solution monitoring: theoretical approach.

In this research, we have a theoretical simple and highly sensitive sodium chloride (NaCl) sensor based on the excitation of Tamm plasmon resonance through a one-dimensional photonic crystal structure. The configuration of the proposed design was, [prism/gold (Au)/water cavity/silicon (Si)/calcium fluoride (CaF)/glass substrate]. The estimations are mainly investigated based on both the optical properties of the constituent materials and the transfer matrix method as well.

Machine learning to reveal an astute risk predictive framework for Gynecologic Cancer and its impact on women psychology: Bangladeshi perspective.

Background: In this research, an astute system has been developed by using machine learning and data mining approach to predict the risk level of cervical and ovarian cancer in association to stress.

Results: For functioning factors and subfactors, several machine learning models like Logistics Regression, Random Forest, AdaBoost, Naïve Bayes, Neural Network, kNN, CN2 rule Inducer, Decision Tree, Quadratic Classifier were compared with standard metrics e.g.

Human bone and amniotic membrane banking in Bangladesh for grafting: the impact of the international atomic energy agency (IAEA) programme.

The idea of establishing a human tissue bank in Bangladesh was started in 1985. However, in 2003, with the active cooperation of international atomic energy agency (IAEA) and Bangladesh Atomic Energy Commission, a tissue bank laboratory was upgraded as a unit for tissue banking and research. Due to increasing demand of allograft, this unit was transformed as an independent institute "Institute of Tissue Banking and Biomaterial Research (ITBBR)" in 2016.

Amnion and collagen-based blended hydrogel improves burn healing efficacy on a rat skin wound model in the presence of wound dressing biomembrane.

Background: A burn wound is one of the most frequent and devastating injuries for patients which requires extensive care. Early treatment of burn wounds improves healing significantly.

Objective: This study was designed to investigate the efficacy of amnion and collagen-based hydrogels on cutaneous burn wound healing in rats with covering membrane.

Characterization of burn wound healing gel prepared from human amniotic membrane and Aloe vera extract.

Background: Skin burn wound is a notable medical burden worldwide. Rapid and effective treatment of burnt skin is vital to fasten wound closure and healing properly. Amniotic graft and Aloe vera are widely used as wound managing biomaterials.

Human tissue banking in Bangladesh: hope for the patients of massive burns, surgical wound and bone associated complications.

Each year throughout Bangladesh, thousands of people suffering from massive burns and surgical wounds require amniotic grafts for transplantation. Additionally, the stricken persons of the country have to embrace bone associated disability for the whole life due to traumatic complications need bone graft to treat. As a result, these two problems are the largest financial burden as this situation not only affect the family of patients but also cripple down national economy.

Fabrication of biocompatible porous scaffolds based on hydroxyapatite/collagen/chitosan composite for restoration of defected maxillofacial mandible bone.

Fabrication of scaffolds from biomaterials for restoration of defected mandible bone has attained increased attention due to limited accessibility of natural bone for grafting. Hydroxyapatite (Ha), collagen type 1 (Col1) and chitosan (Cs) are widely used biomaterials which could be fabricated as a scaffold to overcome the paucity of bone substitutes. Here, rabbit Col1, shrimp Cs and bovine Ha were extracted and characterized with respect to physicochemical properties.

Dataset on significant risk factors for Type 1 Diabetes: A Bangladeshi perspective.

In this article, dataset and detailed data analysis results of Type-1 Diabetes has been given. Now-a-days Type-1 Diabetes is an appalling disease in Bangladesh. Total 306 person data (Case group- 152 and Control Group- 154) has been collected from Dhaka based on a specific questioner.

Estimation of Cross-Immunity Between Drifted Strains of Influenza A/H3N2.

To determine the cross-immunity between influenza strains, we design a novel statistical method, which uses a theoretical model and clinical data on attack rates and vaccine efficacy among school children for two seasons after the 1968 A/H3N2 influenza pandemic. This model incorporates the distribution of susceptibility and the dependence of cross-immunity on the antigenic distance of drifted strains. We find that the cross-immunity between an influenza strain and the mutant that causes the next epidemic is 88%.

Ultrahigh birefringence, ultralow material loss porous core single-mode fiber for terahertz wave guidance.

In this paper, a novel polarization-maintaining single-mode photonic crystal fiber (PCF) has been suggested for terahertz (THz) transmission applications. The reported PCF has five layers of hexagonal cladding with two layers of porous core. The cladding and core territory of the PCF are constituted by circular and elliptical air cavities, accordingly acting as a dielectric medium.

Hybrid photonic crystal fiber in chemical sensing.

Background: In this article, a hybrid photonic crystal fiber has been proposed for chemical sensing. A FEM has been applied for numerical investigation of some propagation characteristics of the PCF at a wider wavelength from 0.7 to 1.

Tissue banking in Bangladesh: 12 years of experience (2003-2014).

Tissue Banking and Biomaterial Research Unit (TBBRU), the only tissue bank of Bangladesh, has been established to create an available supply of human tissue allografts for transplantation in Bangladesh. Since its establishment in 2003, TBBRU strictly follows the guidelines of tissue banking setup by the International Atomic Energy Agency, the European Association of Tissue Banks and the American Association of Tissue Banks. Though started serving from earlier, regular supply of tissue allografts from this bank were documented at the end of 2006.

Association Assessment among Risk Factors and Breast Cancer in a Low Income Country: Bangladesh.

Background: In the low incoming country Bangladesh, breast cancer is second most common neoplasm and is increasing at an alarming rate among females. Lack of awareness and illiteracy are contributory factors for late presentation and therefore mortality.

Purpose: To examine associations of different factors with breast cancer mortality and to raise awareness among the women of society in Bangladesh.

The coexistence or replacement of two subtypes of influenza.

A pandemic subtype of influenza A sometimes replaces but sometimes coexists with the previous seasonal subtype. For example, the 1957 pandemic subtype H2N2 replaced the seasonal subtype H1N1; whereas after 1977 subtypes H1N1 (from the pandemic) and H3N2 continue to coexist. In an attempt to understand these alternatives, a hybrid model for the dynamics of influenza A is formulated.

Variations of Weight of Thyroid Gland in Different Age and Sex Groups of Bangladeshi Cadavers.

A cross sectional descriptive study was designed to find out the difference in weight of the thyroid gland of Bangladeshi people in relation to age and sex. The present study was performed on 70 post mortem human thyroid gland (35 of male and 35 of female) collected from the morgue in the Department of Forensic Medicine, Mymensingh Medical College, Mymensingh by purposive sampling technique. The specimens were collected from Bangladeshi cadavers of age ranging from 10 years to 85 years.

TGF-β/BMP signaling and other molecular events: regulation of osteoblastogenesis and bone formation.

Transforming growth factor-beta (TGF-β)/bone morphogenetic protein (BMP) plays a fundamental role in the regulation of bone organogenesis through the activation of receptor serine/threonine kinases. Perturbations of TGF-β/BMP activity are almost invariably linked to a wide variety of clinical outcomes, i.e.

Effects of gamma irradiation on bacterial microflora associated with human amniotic membrane.

Human amniotic membrane is considered a promising allograft material for the treatment of ocular surface reconstruction, burns, and other skin defects. In order to avoid the transmission of any diseases, grafts should be perfectly sterile. Twenty-five amniotic sacs were collected to determine the microbiological quality of human amniotic membrane, to analyze the radiation sensitivity pattern of the microorganism, and to detect the radiation decimal reduction dose (D₁₀) values.

The evolution of dispersal conditioned on migration status.

We consider a model for the evolution of dispersal of offspring. Dispersal is treated as a parental trait that is expressed conditional upon a parent's own "migration status," that is, whether a parent, itself, is native or nonnative to the area in which it breeds. We compare the evolution of this kind of conditional dispersal to the evolution of unconditional dispersal, in order to determine the extent to which the former changes predictions about population-wide levels of dispersal.

Nukacin ISK-1, a bacteriostatic lantibiotic.

We determined the mode of action of nukacin ISK-1. It did not cause membrane potential dissipation or the efflux of ATP or K(+) ions from the cells of a sensitive bacterial strain; however, it blocked the membrane depolarization activity of nisin. Nukacin ISK-1-treated cells had single arrangements of cells without the formation of a complete septum.

Mapping and identification of the region and secondary structure required for the maturation of the nukacin ISK-1 prepeptide.

The prepeptide NukA of the lantibiotic nukacin ISK-1 consists of an N-terminal leader peptide followed by a propeptide moiety that undergoes post-translational modifications, that is, formation of unusual amino acids by NukM, cleavage of the leader peptide and transport by NukT to yield a mature peptide. To identify the region and conformation required for the maturation of prepeptide, we expressed a series of NukA mutants, mutants with the N-terminus-truncated leader peptide and site-directed mutants with conserved residues in the leader peptide of type A(II) lantibiotics, which were evaluated on the basis of the production of nukacin ISK-1. In addition, the secondary structure data of NukA mutants or fragments were obtained by circular dichroism spectra.

Lantibiotics: diverse activities and unique modes of action.

Lantibiotics are one of the most promising alternative candidates for future antibiotics that maintain their antibacterial efficacy through many mechanisms. Of these mechanisms, some modes of activity have recently been reported, providing opportunities to show these peptides as potential candidates for forthcoming applications. Many findings providing new insight into the detailed molecular activities of numerous lantibiotics are constantly being uncovered.

Lantibiotics: insight and foresight for new paradigm.

Lantibiotics are a unique type of antimicrobial peptide produced by a large number of gram-positive bacteria that contain unusual amino acids, such as lanthionine and dehydrated amino acids. Ribosomally synthesized lantibiotic prepeptide consists of an N-terminal leader peptide followed by a C-terminal propeptide moiety that undergoes several post-translational modification events to yield a biologically active lantibiotic. Research on lantibiotics has drawn much attention in recent years and has undergone extensive progress as a step forward to the next paradigm.