Publications by authors named "Asad Jafri"

Article Synopsis
  • Dacryocystorhinostomy (DCR) is a surgery performed on patients with chronic dacryocystitis to relieve blocked tears, and this study aimed to link postoperative success to the level of inflammation in biopsies.
  • Twenty-five patients underwent DCR, and their biopsy results were graded for inflammation, showing that severe inflammation was present in a majority of cases.
  • Despite high inflammation scores (CIS), the DCR was successful in 96% of patients after six months, indicating that inflammation levels may not significantly affect surgical outcomes, warranting further research for confirmation.
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Article Synopsis
  • Colorectal cancer (CRC) accounts for about 10% of global cancer cases and deaths; AI-supported methods are being considered to assist pathologists with the increasing workload of examining lymph nodes post-surgery.
  • The study involved analyzing digital images of lymph nodes from 165 CRC cases, using AI software to detect tumor deposits, and it showed high accuracy with 84% true positives and 88.5% true negatives.
  • Results indicated a sensitivity of 89% and specificity of 83.1%, suggesting AI could support pathologists, and further research with larger samples is recommended to validate these findings.
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Background: Neuroendocrine tumors (NETs) represent a diverse group of neoplasms that arise from neuroendocrine cells, with Ki-67 immunostaining serving as a crucial biomarker for assessing tumor proliferation and prognosis. Accurate and reliable quantification of Ki-67 labeling index is essential for effective clinical management.

Methods: We aimed to evaluate the performance of open-source/open-access deep learning cloud-native platform, DeepLIIF (https://deepliif.

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Objective: The objective of the study is to report an unusual rise in cases of assault with ocular injury and their medicolegal implications presenting in an eye department of a tertiary care hospital during COVID-19 lockdown.

Materials And Methods: A retrospective, observational case series was conducted in the Department of Ophthalmology, Abbasi Shaheed Hospital, Karachi. Data were retrieved from the medicolegal records of the patients from April 1, 2019, to July 31, 2019, and similar months in 2020.

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Background: Scleromalacia perforans is a rare ocular manifestation of rheumatoid arthritis which can potentially lead to blindness and is a late consequence in the course of the disease. It is an unusual finding for it to be present in a patient with joint pain without any rheumatologic progression of disease.

Case Presentation: We describe a rare case of scleromalacia perforans and orbital inflammatory disease in a 40-year-old Pakistani woman with apparently no associated rheumatologic deformity.

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Fibro-osseous pseudotumor of the digit is rare benign lesion of subcutaneous tissue which is thought to be reactive process as a result of repeated trauma. We report a case of an ulcerated lesion of skin of middle finger, clinically thought to be leishmaniasis which after punch biopsy followed by excision turned out to be fibrosseous pseudotumor. Diagnosis of fibro-osseous pseudotumor requires immense precision as it can clinically mimic unungal exostosis and can sometimes be misinterpreted clinically and radiologically as myositis ossificans.

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