Publications by authors named "Asaad Ma Babker"
Article Synopsis
- * Conducted with 216 women, the research analyzed genetic polymorphisms using PCR, revealing a high prevalence of certain genotypes among women with RPL and differences in allele frequency between cases and controls.
- * Findings suggest a potential association between the studied genetic variants and RPL, though statistical significance was not established for most comparisons, indicating a need for further research.
Polycystic ovary syndrome (PCOS) is a complex endocrine disorder that affects a substantial percentage of women, estimated at around 9-21%. This condition can lead to anovulatory infertility in women of childbearing age and is often accompanied by various metabolic disturbances, including hyperandrogenism, insulin resistance, obesity, type-2 diabetes, and elevated cholesterol levels. The development of PCOS is influenced by a combination of epigenetic alterations, genetic mutations, and changes in the expression of non-coding RNAs, particularly microRNAs (miRNAs).
View Article and Find Full Text PDFAlzheimer's disease (AD) and brain tumors are debilitating neurological conditions that pose significant challenges in current medical practices. Existing treatment options for AD primarily focus on symptom management, and brain tumors often require aggressive therapeutic approaches. Novel disease-modifying strategies and therapeutic agents are urgently needed to address the underlying causes of AD pathogenesis and improve brain tumor management.
View Article and Find Full Text PDFColorectal cancer is a sporadic, hereditary, or familial based disease in its origin, caused due to diverse set of mutations in large intestinal epithelial cells. Colorectal cancer (CRC) is a common and deadly disease that accounts for the 4 worldwide highly variable malignancy. For the early detection of CRC, the most common predictive biomarker found endogenously are KRAS and ctDNA/cfDNA along with methylated DNA.
View Article and Find Full Text PDFObjective: The purpose of this study was to perform hematological and molecular analyses of the HbS allele of the hemoglobin subunit beta gene in the Sudanese population.
Methods: This was a descriptive cross-sectional study. Hematological parameters and fetal hemoglobin (HbF) levels were assessed in all participants.
<b>Background and Objective:</b> Coronavirus disease (COVID-19) has spread throughout the world. Several studies have indicated that ABO blood group polymorphism could be connected to COVID-19 vulnerability and clinical outcomes, nevertheless, the findings are debatable. The aim of this study was to determine the most blood groups susceptible for COVID-19 infection among Sudanese patients suffering from different chronic diseases.
View Article and Find Full Text PDFAim: The objective of the current study was to assess the influence of oral multivitamins supplementation on some oxidative stress parameters (serum Vitamin A, C, E, Zinc, Malondialdehyde (MDA)) and lipid profile among Sudanese patients with type- 2 diabetes mellitus (T2DM).
Material And Method: Three hundred Sudanese patients with T2DM and Hundred healthy subjects (control group) were enrolled in this cross-sectional study. Blood was collected after overnight fasting for 10-12 hrs.