Publications by authors named "Asa Danielsson Borssen"
Background: Cleavage products from collagen formation and degradation hold potential as first-line biomarkers for the risk of advanced fibrosis in patients with metabolic dysfunction-associated steatotic liver disease (MASLD). Here, we evaluated the performance of PRO-C3, PRO-C6, C4M, PRO-C18L, and the clinical score ADAPT (age, diabetes, PRO-C3, and platelet count) to detect patients with an LSM >8 kPa or >12 kPa in comparison to the Fibrosis-4 Index (FIB-4).
Methods: Serum from patients with MASLD (n = 269) from six Swedish University Hospitals was analyzed using enzyme-linked immunosorbent assay-based methods.
Purpose: Surveillance for hepatocellular carcinoma (HCC) is recommended in at-risk patients, but its effectiveness in Western populations has been questioned. The purpose was to evaluate the effect of surveillance in patients with HCC in a Northern European setting.
Patients And Methods: Data on patients diagnosed with HCC between 2009 and 2019 were collected from the nationwide Swedish National Registry for Tumors of the Liver and Bile Ducts (SweLiv).
Article Synopsis
- The study aimed to analyze the epidemiology, long-term prognosis, and causes of death among 634 patients with autoimmune hepatitis (AIH) in Sweden.
- Results showed a point prevalence of 17.3 cases per 100,000 people and an annual incidence of 1.2 cases per 100,000 from 1990 to 2009, with a median survival of 11.3 years post-diagnosis.
- Findings indicated that while men were diagnosed earlier and died younger, overall survival rates and liver-related deaths were similar between genders, with cirrhosis at diagnosis significantly linked to poorer outcomes.
Introduction: Autoimmune hepatitis (AIH) is a liver disease that primarily affects women. Many become ill during childbearing age, and medication can be lifelong. Few studies exist on pregnancy outcome in women with AIH.
View Article and Find Full Text PDFObjectives: Cirrhosis is a well-known risk factor for hepatocellular cancer, but the true risk in autoimmune hepatitis (AIH) is scarcely studied. Other cancers may arise after prolonged use of immune-modulating drugs. The aim of this study was to investigate the cancer risk in a large cohort of AIH patients.
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