Publications by authors named "Asa Augustinsson"
Article Synopsis
- The study aims to enhance the accuracy of 16S rRNA gene amplification and sequencing for identifying bacteria in clinical samples, addressing issues like false positives and interference from human DNA.
- Various DNA extraction methods and primer sets were tested on tissue samples from patients with suspected infections, showing that bacterial enrichment improved sensitivity.
- The research concluded that careful optimization of extraction techniques and primer choices can significantly improve the effectiveness of molecular diagnostics alongside traditional tissue culture methods.
To investigate the management of patients with community-acquired pneumonia (CAP) treated in hospital in Sweden, a multicentre retrospective cohort study was performed with medical record review of 982 patients (mean age 63 y) at 17 departments of infectious diseases at hospitals in Sweden. Information on antimicrobial therapy, demographic characteristics, comorbid conditions, physical examination findings, and laboratory and microbiological test results were recorded. Outcome measures were in-hospital mortality and length of hospital stay (LOS).
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