Publications by authors named "As D"

The One Health approach, which emphasizes the interconnection between human, animal, plant, and environmental health, has gained significant attention as a framework for addressing global health challenges. This study presents a thorough bibliometric analysis of One Health research, utilizing the Web of Science Core Collection database, covering the period from 1989 to 2024. The analysis uncovers a substantial increase in scientific output over the years, reflecting the growing importance of this interdisciplinary field.

View Article and Find Full Text PDF

Lingonberry is a common wild berry that is often sold as jams and beverages. It naturally contains high amounts of the weak acid preservative benzoic acid making it an interesting ingredient for shelf-life extension. Despite this, their use as a raw ingredient is limited by the inherently intense sour taste.

View Article and Find Full Text PDF

The study focused on the composition of soil mesofauna within changing cropping systems influenced by urbanization in Bengaluru, Karnataka, India during the rabi season of 2020 (October)-2021 (February). Four major cropping systems, namely pulses (red gram), vegetables (tomato and ridge gourd), horticulture (grapes and chickoo), and agriculture + horticulture crops, (coconut + fodder plantation), were examined across urban, peri-urban, and rural zones in Bengaluru. The research uncovered a total of 714 individuals belonging to 16 different soil mesofauna taxa among the crops studied.

View Article and Find Full Text PDF

It is of interest to investigate the effectiveness of a mindfulness-based stress reduction program on stress and salivary cortisol among substance abuse patients. There were 60 drug addicts who were receiving treatment at the addiction centre. Samples are divided into 30 drug abuse patient experimental and 30 substance abuse patient control groups using the simple random sampling approach.

View Article and Find Full Text PDF

Healthcare workers (HCWs) who come into contact with tuberculosis (TB) patients are at elevated risk of TB infection and disease. The collection and handling of sputum samples for TB diagnosis poses exposure risks to HCWs, particularly in settings where aerosol containment is limited. An alternative sample collection method, tongue swabbing, was designed to help mitigate this risk, and is under evaluation in multiple settings.

View Article and Find Full Text PDF

The lack of internal polarization fields in cubic group-III nitrides makes them promising arsenic-free contenders for next-generation high-performance electronic and optoelectronic applications. In particular, cubic InGaN semiconductor alloys promise band gap tuning across and beyond the visible spectrum, from the near-ultraviolet to the near-infrared. However, realization across the complete composition range has been deemed impossible due to a miscibility gap corresponding to the amber spectral range.

View Article and Find Full Text PDF
Article Synopsis
  • Changes in muscle MRI metrics over five years correlate with clinical outcomes in facioscapulohumeral muscular dystrophy (FSHD), indicating their potential as prognostic biomarkers in trials.
  • The study involved 105 patients, who underwent MRI assessments and clinical evaluations, showing a median MRI compound score increase of 2.0% and small changes in clinical scores.
  • Subgroups of patients with specific MRI characteristics exhibited the most significant radiological progression, highlighting the importance of targeted assessments in understanding the disease's impact.
View Article and Find Full Text PDF

Background: Myotonic dystrophy type 1 (DM1) is an incurable multisystem disease caused by a CTG-repeat expansion in the DM1 protein kinase (DMPK) gene. The OPTIMISTIC clinical trial demonstrated positive and heterogenous effects of cognitive behavioral therapy (CBT) on the capacity for activity and social participations in DM1 patients. Through a process of reverse engineering, this study aims to identify druggable molecular biomarkers associated with the clinical improvement in the OPTIMISTIC cohort.

View Article and Find Full Text PDF
Article Synopsis
  • High-latitude surface energy budgets (SEBs) are important for understanding land-climate interactions in the Arctic, but uncertainties in their predictions remain.
  • A study analyzed SEB observations from 1994 to 2021 and found that vegetation type is a key predictor of SEB components during Arctic summers, often matching or exceeding differences seen between vegetation and glacier surfaces.
  • The study also revealed that the timing of SEB fluxes varies significantly with vegetation type, affecting snow-cover dynamics and suggesting that better representations of Arctic vegetation in models could enhance future Earth system predictions.
View Article and Find Full Text PDF

We present a spectrophotometer (optical density meter) combined with electromagnets dedicated to the analysis of suspensions of magnetotactic bacteria. The instrument can also be applied to suspensions of other magnetic cells and magnetic particles. We have ensured that our system, called MagOD, can be easily reproduced by providing the source of the 3D prints for the housing, electronic designs, circuit board layouts, and microcontroller software.

View Article and Find Full Text PDF

Quantum well (QW) heterostructures have been extensively used for the realization of a wide range of optical and electronic devices. Exploiting their potential for further improvement and development requires a fundamental understanding of their electronic structure. So far, the most commonly used experimental techniques for this purpose have been all-optical spectroscopy methods that, however, are generally averaging in momentum space.

View Article and Find Full Text PDF

Background: The European OPTIMISTIC clinical trial has demonstrated a significant, yet heterogenous effect of Cognitive Behavioural Therapy (CBT) for Myotonic Dystrophy type 1 (DM1) patients. One of its remaining aims was the assessment of efficacy and adequacy of clinical outcome measures, including the relatively novel primary trial outcome, the DM1-Activ-c questionnaire.

Objectives: Assessment of the relationship between the Rasch-built DM1-Activ-c questionnaire and 26 commonly used clinical outcome measurements.

View Article and Find Full Text PDF

The chemoselective reduction of diaryl imines in the presence of competitively reducible groups is uniquely accessed through precise control of reaction and irradiation time by continuous flow visible light photoredox catalysis. The method enables the mild and efficient transfer hydrogenation of diaryl imines in the presence of sensitive functionality including halides, ester, ketone, and cyano groups. The flow protocol is efficient, rapid (>98% conversion within 9 min) and readily scaled to deliver multigram quantities of amine products in high purity.

View Article and Find Full Text PDF

In recent decades, meltwater runoff has accelerated to become the dominant mechanism for mass loss in the Greenland ice sheet. In Greenland's high-elevation interior, porous snow and firn accumulate; these can absorb surface meltwater and inhibit runoff, but this buffering effect is limited if enough water refreezes near the surface to restrict percolation. However, the influence of refreezing on runoff from Greenland remains largely unquantified.

View Article and Find Full Text PDF

Greenland Ice Sheet mass loss has recently increased because of enhanced surface melt and runoff. Since melt is critically modulated by surface albedo, understanding the processes and feedbacks that alter albedo is a prerequisite for accurately forecasting mass loss. Using satellite imagery, we demonstrate the importance of Greenland's seasonally fluctuating snowline, which reduces ice sheet albedo and enhances melt by exposing dark bare ice.

View Article and Find Full Text PDF
Article Synopsis
  • A new method using visible light and a catalyst allows for the selective reduction of imines, which are compounds derived from aldehydes or ketones, employing EtN as a hydrogen source.
  • This method can effectively reduce imines even when other sensitive groups, like nitriles or halides, are present in the molecule.
  • The continuous-flow technique makes it easier to scale up the reaction for larger production, and various experiments confirmed how EtN functions in this process.
View Article and Find Full Text PDF

Meltwater runoff from the Greenland ice sheet surface influences surface mass balance (SMB), ice dynamics, and global sea level rise, but is estimated with climate models and thus difficult to validate. We present a way to measure ice surface runoff directly, from hourly in situ supraglacial river discharge measurements and simultaneous high-resolution satellite/drone remote sensing of upstream fluvial catchment area. A first 72-h trial for a 63.

View Article and Find Full Text PDF

Background: Vaccination of human immunodeficiency virus (HIV)-infected infants with bacille Calmette-Guérin (BCG) is contraindicated. HIV-exposed newborns need a new tuberculosis vaccination strategy that protects against tuberculosis early in life and avoids the potential risk of BCG disease until after HIV infection has been excluded.

Methods: This double-blind, randomized, controlled trial compared newborn MVA85A prime vaccination (1 × 108 PFU) vs Candin® control, followed by selective, deferred BCG vaccination at age 8 weeks for HIV-uninfected infants and 12 months follow-up for safety and immunogenicity.

View Article and Find Full Text PDF

The surface energy balance (SEB) is essential for understanding the coupled cryosphere-atmosphere system in the Arctic. In this study, we investigate the spatiotemporal variability in SEB across tundra, snow and ice. During the snow-free period, the main energy sink for ice sites is surface melt.

View Article and Find Full Text PDF

Unlabelled: The rapid drainage of supraglacial lakes injects substantial volumes of water to the bed of the Greenland ice sheet over short timescales. The effect of these water pulses on the development of basal hydrological systems is largely unknown. To address this, we develop a lake drainage model incorporating both (1) a subglacial radial flux element driven by elastic hydraulic jacking and (2) downstream drainage through a linked channelized and distributed system.

View Article and Find Full Text PDF

The diagnostic yield of pulmonary tuberculosis (TB) by sputum induction (SI) at the first point of contact with health services, conducted in all patients with suspected TB regardless of the ability to expectorate spontaneously, has not been evaluated. We compared the diagnostic yield of SI to routine sputum collection in a South African community setting. Ambulatory patients with suspected TB provided a 'spot' expectorated sputum sample, an SI sample by hypertonic (5 %) saline nebulization, and early morning expectorated sputum sample.

View Article and Find Full Text PDF

Introduction: Anthropological studies have document differences in craniofacial features as well as in body characteristics among different populations. The variations in the facial morphology arise through a differential growth and they help us in distinguishing one person from another. These are controlled by a number of factors which include genetic heritage, climate and environment in which we live.

View Article and Find Full Text PDF

Background: Effective infection control measures are essential to reduce tuberculosis (TB) transmission in domestic, workplace, and health care settings. Acceptability of infection control measures is key to patient adherence.

Methods: We used a prospective questionnaire study to determine knowledge and acceptability of potential patient-specific TB infection control measures in a rural South African community.

View Article and Find Full Text PDF

We described the population pharmacokinetics of moxifloxacin and the effect of high-dose intermittent rifapentine in patients with pulmonary tuberculosis who were randomized to a continuation-phase regimen of 400 mg moxifloxacin and 900 mg rifapentine twice weekly or 400 mg moxifloxacin and 1,200 mg rifapentine once weekly. A two-compartment model with transit absorption best described moxifloxacin pharmacokinetics. Although rifapentine increased the clearance of moxifloxacin by 8% during antituberculosis treatment compared to that after treatment completion without rifapentine, it did not result in a clinically significant change in moxifloxacin exposure.

View Article and Find Full Text PDF