Transgenic zebrafish (Danio rerio) as an emerging model system in ecotoxicology and toxicology: Historical review, recent advances, and trends.

Zebrafish (Danio rerio) is an alternative model system for drug screening, developing new products, and assessing ecotoxic effects of pollutants and biomonitor species in environmental risk assessment. However, the history and current use of transgenic zebrafish lines in ecotoxicology and toxicology studies remain poorly explored. Thus, the present study aimed to summarize and discuss the existing data in the literature about the applications of transgenic zebrafish lines in ecotoxicology and toxicology.

Toxicity of plant-based silver nanoparticles to vectors and intermediate hosts: Historical review and trends.

Green nanoparticles (GNPs), mainly green silver nanoparticles (Ag NPs), have been recommended as sustainable and eco-friendly technologies to control vectors and intermediate hosts. The aim of the current study is to carry out a historical and systematic literature review about the use of green plant-based Ag NPs (GP-Ag NPs) to control medically important mosquito, tick and gastropods. Data about the number of studies published per year, geographical distribution of studies (mailing address of the corresponding author), synthesis type (plant species, plant structure and extract types), physicochemical properties of GP-Ag NPs, experimental designs, developmental stages and the toxic effects on mosquitoes, ticks and gastropods were summarized and discussed.

Micronucleus test and nuclear abnormality assay in zebrafish (Danio rerio): Past, present, and future trends.

Nuclear abnormality (NA) assay in fish has been widely applied for toxicity risk assessment under field and laboratory conditions. The zebrafish (Danio rerio) has become a suitable model system for assessing the NA induced by pollutants. Thus, the current study aimed to summarize and discuss the literature concerning micronucleus (MN) and other NA in zebrafish and its applications in toxicity screening and environmental risk assessment.

Zebrafish (Danio rerio) using as model for genotoxicity and DNA repair assessments: Historical review, current status and trends.

Genotoxic pollutants lead to both DNA damage and changes in cell repair mechanisms. Selecting suitable biomonitors is a fundamental step in genotoxicity studies. Thus, zebrafish have become a popular model used to assess the genotoxicity of different pollutants in recent years.

Zebrafish as an Emerging Model System in the Global South: Two Decades of Research in Brazil.

The zebrafish () is an emerging model system in several research areas worldwide, especially in the Global South. In this context, the present study revised the historical use and trends of zebrafish as experimental models in Brazil. The data concerning the bibliometric parameters, research areas, geographic distribution, experimental design, zebrafish strain, and reporter lines, as well as recent advances were revised.