Publications by authors named "Aryan R Ganjo"
Article Synopsis
- This study examines the effectiveness of vitamin C and vitamin D in countering biofilms, which hinder treatment effectiveness and foster antibiotic resistance in pathogens.
- Researchers used molecular docking analyses with AutoDock Vina to determine how well these vitamins bind to proteins related to biofilm formation.
- Results indicated that vitamin D has a stronger binding affinity than vitamin C, suggesting its potential as a promising anti-biofilm agent to be used in conjunction with antibiotics, pending further validation through molecular dynamics simulations.
Article Synopsis
- * Researchers found that a significant percentage of P. aeruginosa isolates were capable of synthesizing titanium dioxide nanoparticles (TiONPs), which were characterized through various scientific techniques.
- * The biosynthesized TiONPs demonstrated strong antibacterial properties and were effective in reducing biofilm formation, especially when used in combination with specific antibiotics, highlighting their potential as alternative therapies against antibiotic-resistant bacteria.
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the main causes of community- and hospital-acquired infections. The expression of virulence genes in S. aureus is arranged by regulators like the accessory gene regulator (agr).
View Article and Find Full Text PDFBackground: Escherichia coli (E. coli) is a multidrug resistant opportunistic pathogen that can cause secondary bacterial infections in patients with COVID-19. This study aimed to determine the antimicrobial resistance profile of E.
View Article and Find Full Text PDFCombination therapies have been studied by many researchers using different techniques and methods to solve some solid drug problems and improve more effective treatments for humans and animals. One of the more significant findings to emerge from this study is that the combination of pharmaceutical agents by using pharmaceutical deep eutectic solvents (PDESs) in order to produce dual action drugs and reduce the drug resistance. The major objective of this study was to investigate the dual functionality of drugs (antioxidant and antibacterial activity) via the principle of PDESs.
View Article and Find Full Text PDFBackground And Objectives: The resistance of to antibiotics offers a significant challenge in the treatment of patients. This study aimed to investigate the antimicrobial resistance profile, biofilm-specific antimicrobial resistance genes, and genetic diversity of recovered from clinical samples.
Materials And Methods: Totally 47 non-duplicate isolates of were recovered from various clinical samples.
Acinetobacter baumannii is a pathogen that has caused rising concerns within healthcare facilities in recent years. As antibiotic overuse and resistance rise, natural remedies with the potential have received attention as antibiotics that might have fewer side effects and lower resistance. Glycyrrhiza glabra was used to investigate its effects on A.
View Article and Find Full Text PDFLong non-coding RNAs (lncRNAs) are a heterogeneous group of ncRNAs with characteristic size of more than 200 nucleotides. An increasing number of lncRNAs have been found to be dysregulated in many human diseases particularly cancer. However, their role in carcinogenesis is not precisely understood.
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