Improved Neural Differentiation of Human-induced Pluripotent Stem Cell [hiPSCs] on a Novel Polyurethane-based Scaffold Containing Iron Oxide Nanoparticles [FeO NPs].

Background: Repair of the nervous system in humans has always been complicated and faced difficulties. Cell transplantation approaches using biocompatible scaffolds might be an attractive therapeutic strategy for neuronal regeneration.

Objective: We designed a cell delivery platform based on polyurethane [PU] and modified it with iron oxide nanoparticles [FeO NPs] for neural induction of human-induced pluripotent stem cells [hiPSC].