Publications by authors named "Arwed Ludwig"
Aim: The aim of this study was to test the hypothesis that recombinant human growth and differentiation factor-5 (rhGDF-5) in combination with a beta-tricalcium phosphate (beta-TCP) scaffold material results in superior bone formation in sinus floor augmentations in miniature pigs compared with a particulated autogenous bone graft combined with the scaffold material.
Material And Methods: Six adult female Goettingen minipigs underwent a maxillary sinus floor augmentation procedure. In a split-mouth design, the sinus floors were augmented with beta-TCP mixed with autogenous cortical bone chips, in a ratio of approximately 1 : 1, on one side.
Innovative muscle stimulation techniques have become alternatives for therapy of obstructive sleep apnea syndrome breathing disorders. In group I, an individually shaped mouth floor electrode (IME) and in group II, an individually adaptable multi-point electrode (MPE) on a silicone carrier has been used for electromyostimulation (EMS) therapy in patients with obstructive sleep apnea. The enoral-cutaneous EMS was carried out with the low-frequency stimulation apparatus I-pulse over a period of 8 weeks, two times daily for 30 min during daytime hours only.
View Article and Find Full Text PDFAim: The aim of this study was to test the hypothesis that recombinant human growth and differentiation factor-5 (rhGDF-5) enhances bone formation in sinus floor augmentations in miniature pigs.
Material And Methods: The maxillary sinus floors in 12 adult female Goettingen minipigs were augmented with beta-tricalcium phosphate (beta-TCP) on one side. The contralateral test side was augmented using two concentrations of rhGDF-5 (400 microg rhGDF-5/g beta-TCP; 800 microg rhGDF-5/g beta-TCP) delivered on beta-TCP (six animals each).