Combatting synthetic dye toxicity through exploring the potential of lignin peroxidase from Pseudomonas fluorescence LiP RL5.

Untreated release of toxic synthetic and colorful dyes is a serious threat to the environment. Every year, several thousand gallons of dyes are being disposed into the water resources without any sustainable detoxification. The accumulation of hazardous dyes in the environment poses a severe threat to the human health, flora, fauna, and microflora.

Bio-inspired multifunctional and reusable LiP@MFO-GO and LiP@MFO-Chit hybrid enzyme complexes for efficient degradation of melanin.

Melanin is a complex brown pigment, primarily responsible for the skin pigmentation. Therefore, cosmetic industries have always been in search of potent oxidative enzymes useful for melanin degradation, and to promise a fair complexion after using their products. In the present study, lignin peroxidase from Pseudomonas fluorescence LiP-RL5 isolate has been immobilized on super-paramagnetic nanoparticles to enhance its stability and reusability.

Guardians of the Gut: Harnessing the Power of Probiotic Microbiota and Their Exopolysaccharides to Mitigate Heavy Metal Toxicity in Human for Better Health.

Heavy metal pollution is a significant global health concern, posing risks to both the environment and human health. Exposure to heavy metals happens through various channels like contaminated water, food, air, and workplaces, resulting in severe health implications. Heavy metals also disrupt the gut's microbial balance, leading to dysbiosis characterized by a decrease in beneficial microorganisms and proliferation in harmful ones, ultimately exacerbating health problems.

Screening for Multifarious Plant Growth Promoting and Biocontrol Attributes in Strains Isolated from Indo Gangetic Soil for Enhancing Growth of Rice Crops.

Multifarious plant growth-promoting strains recovered from rhizospheric soils of the Indo Gangetic plains (IGPs) were identified as MNNITSR2 and MNNITSR18 based on their biochemical characteristics and 16S rDNA gene analysis. Both strains exhibited the ability to produce IAA, siderophores, ammonia, lytic enzymes, HCN production, and phosphate solubilization capability and strongly inhibited the growth of phytopathogens such as and in vitro. In addition, these strains are also able to grow at a high temperature of 50 °C and tolerate up to 10-15% NaCl and 25% PEG 6000.

Microbial Exopolysaccharide Composites in Biomedicine and Healthcare: Trends and Advances.

Microbial exopolysaccharides (EPSs), e.g., xanthan, dextran, gellan, curdlan, etc.

Municipal Wastewater Connection for Water Crisis and Jaundice Outbreaks in Shimla City: Present Findings and Future Solutions.

The felicitous tourist destination "Hills Queen" and the capital city of Himachal Pradesh, an enticing state in the Himalayan region, are met with water crisis every year and jaundice outbreaks occasionally. In 2016, there was a severe jaundice outbreak in Shimla city. In a contemporaneous investigation, we attempted to trace out the possible reason for these crises in Shimla.

Xylitol production by Pseudomonas gessardii VXlt-16 from sugarcane bagasse hydrolysate and cost analysis.

Xylitol is a well-known sugar alcohol with exponentially rising market demand due to its diverse industrial applications. Organic agro-industrial residues (OAIR) are economic alternative for the cost-effective production of commodity products along with addressing environmental pollution. The present study aimed to design a process for xylitol production from OAIR via microbial fermentation with Pseudomonas gessardii VXlt-16.

Quantum dot synthesis from waste biomass and its applications in energy and bioremediation.

Quantum dots (QDs) are getting special attention due to their commendable optical properties and applications. Conventional metal-based QDs have toxicity and non-biodegradability issues, thus it becomes necessary to search for renewable precursor molecules for QDs synthesis. In recent years, biomass-based carbon rich QDs (CQDs) have been introduced which are mainly synthesised via carbonization (pyrolysis and hydrothermal treatment).

Fluorescent xylitol carbon dots: A potent antimicrobial agent and drug carrier.

Biomolecular carbon dots (CDs) have immense potential for various industries due to exceptional bioactivity, biocompatibility, low toxicity, and biodegradability. In the present work xylitol (Xlt), a natural sweetener produced by microbial fermentation of sugarcane bagasse (71.98% conversion) has been used for CDs preparation by microwave-assisted carbonization in the presence of ethylene diamine (EDA).

Cost-effective production of biocatalysts using inexpensive plant biomass: a review.

Enzymes are the complex protein moieties, catalyze the rate of chemical reactions by transforming various substrates to specific products and play an integral part in multiple biochemical cycles. Advancement in enzyme research and its integration with industries have reformed the biotech industries. It provides a superior monetary and ecological exchange to traditional material measures in an efficient and environmentally sustainable manner.

Fabrication of thermostable and reusable nanobiocatalyst for dye decolourization by immobilization of lignin peroxidase on graphene oxide functionalized MnFeO superparamagnetic nanoparticles.

In view of the potential applications of immobilized enzymes, partially purified Lignin Peroxidase (LiP) from Pseudomonas fluorescens LiP-RL5 was immobilized on Graphene Oxide functionalized MnFeO nanoparticles (10 nm, synthesized by sol-gel auto-combustion) to fabricate a new hyperactive and thermostable nanobiocatalyst and thereafter characterized by using standard techniques. Immobilized LiP was quite stable at 50 °C with the half-life of 14 h and showed higher tolerance towards various metal ions and solvents than free LiP. Immobilized LiP retained 50% of enzyme activity even after nine consecutive runs.

Green synthesis of silver nanoparticles using methanolic fruit extract of and their antimicrobial potential against human bacterial pathogens.

Plant-based synthesis of nanoparticles has generated worldwide interest because of cost-effectiveness, eco-friendly nature and plethora of applications. In the present investigation, antimicrobial potential of silver nanoparticles (AgNPs) of methanolic extract of fruit has been investigated. Agar well diffusion method was used for determining antimicrobial activity of solvent extracts (.

Genotypic background of the recipient plant is crucial for conferring RB gene mediated late blight resistance in potato.

Background: Late blight, caused by oomycetes pathogen Phytophthora infestans (Mont.) de Bary, is the most devastating potato disease in the world. RB gene from Solanum bulbocastanum has been shown to impart broad spectrum resistance against P.

Does DcR1 (TNF-related apoptosis-inducing-ligand Receptor 3) have any role in human AMD pathogenesis?

It has been postulated that there is a link between age related degenerative diseases and cancer. The TNF-related apoptosis-inducing ligand (TRAIL) has been shown to selectively kill tumor cells by binding to pro-apoptotic and anti-apoptotic receptors. Our aim was to study the levels of anti-apoptotic receptor (DcR1) in age related macular degeneration (AMD) and controls.

CC chemokine receptor-3 as new target for age-related macular degeneration.

CC chemokine receptor-3 (CCR3) is involved in angiogenic processes. Recently, CCR3 was accounted to participate in choroidal neovascularization (CNV) and CCR3 targeting was reported to be superior to standard antivascular endothelial growth factor-A (VEGF-A) administration when tested in an artificially induced CNV in animals. As human CCR3 studies are lacking in age-related macular degeneration (AMD) patients we sought to determine if CCR3 has any association with inflammatory processes that occur in CNV.