Role of CT Perfusion in Identifying the Core and the Potentially Salvageable Penumbra in Patients with Acute Non Haemorrhagic Stroke - Experience at Tertiary Care Center.

Objectives: To evaluate the role of CT Perfusion in Identifying the core and the potentially salvageable penumbra in brain infarcts by observing perfusion maps (CBV, CBF and MTT). Also to identify patients who would benefit from reperfusion therapy and to evaluate the feasibility of identifying the penumbra on noncontrast CT vide comparison with perfusion maps.

Materials And Methods: A prospective study of 50 patients who presented with acute onset neurological deficit within 6 hours of symptom onset and in whom initial NCCT revealed no evidence of cerebral hemorrhage; evaluated with CT Perfusion was done at tertiary care center in 1 calender year 2014.

Inflationary spacetimes are incomplete in past directions.

Many inflating spacetimes are likely to violate the weak energy condition, a key assumption of singularity theorems. Here we offer a simple kinematical argument, requiring no energy condition, that a cosmological model which is inflating--or just expanding sufficiently fast--must be incomplete in null and timelike past directions. Specifically, we obtain a bound on the integral of the Hubble parameter over a past-directed timelike or null geodesic.