Publications by authors named "Arushi Tiwari"
Glioblastoma (GBM) is a lethal brain tumor with limited therapeutic options. Bi-specific killer cell engagers (BiKEs) are novel immunotherapies designed to engage natural killer (NK) cells against cancer. We designed a BiKE molecule consisting of a single-domain CD16 antibody, an interleukin-15 linker, and a single-chain variable antibody against the glioma-associated antigen interleukin 13 receptor alpha 2 (IL13Rα2).
View Article and Find Full Text PDFCOVID-19: An Accelerator for Global Plastic Consumption and Its Implications.
J Environ Public Health
October 2022
Plastic has been ingrained in our society. Repercussions on the usage of nonbiodegradable plastics and their problems have been recently realized. Despite its detrimental environmental impact, the COVID-19 epidemic has compelled worldwide citizens to increase their plastic use due to affordability and availability.
View Article and Find Full Text PDFArticle Synopsis
- Enterococcus faecium is a dangerous bacterium with no current treatments or vaccines, prompting research into a new vaccine design.
- The study focused on a specific protein, PBP 5, to identify key epitopes for immune responses, ultimately selecting multiple B and T cell epitopes for a novel chimeric vaccine.
- Preliminary results show the developed vaccine is stable, effective, and capable of triggering a strong immune response, paving the way for future experimental trials.