The evolving landscape of personalized medicine necessitates a shift from traditional therapeutic interventions towards precision-driven approaches. Embracing this paradigm, our research probes the therapeutic efficacy of the aqueous crude extract (ACE) of Calocybe indica in cervical cancer treatment, merging botanical insights with advanced molecular research. We observed that ACE exerts significant influences on nuclear morphology and cell cycle modulation, further inducing early apoptosis and showcasing prebiotic attributes.
View Article and Find Full Text PDFMicroorganisms are integral components of ecosystems, exerting profound impacts on various facets of human life. The recent United Nations General Assembly (UNGA) Science Summit emphasized the critical importance of comprehending the microbial world to address global challenges, aligning with the United Nations Sustainable Development Goals (SDGs). In agriculture, microbes are pivotal contributors to food production, sustainable energy, and environmental bioremediation.
View Article and Find Full Text PDFWith the global population explosion, the need for increasing crop productivity is reaching its peak. The significance of organic means of cultivation including biofertilizers and biopesticides is undeniable in this context. Over the last few decades, the use of rhizobacteria to induce crop productivity has gained particular interest of researchers.
View Article and Find Full Text PDFThe rapid growth in the population, industrial developments, and climate change over the century have contributed to a significant rise in aquatic pollution leading to a scarcity of clean, reliable, and sustainable water sources and supply. Exposure through ingestion, inhalation, and dermal absorption of organic/inorganic compounds such as heavy metals, pharmaceuticals, dyes, and persistent organic pollutants (POPs) discharged from municipalities, hospitals, textile industries, food, and agricultural sectors has caused adverse health outcomes in aquatic and terrestrial organisms. Owing to the high surface area, photocatalytic activity, antimicrobial, antifouling, optical, electronic, and magnetic properties, the application of nanotechnology offers unique opportunities in advanced wastewater management strategies over traditional approaches.
View Article and Find Full Text PDFThe data represents the bacterial community profile obtained through metagenomic sequencing of soil sample, collected from the 'Rarh' region of West Bengal, which is characterized by the lateritic badlands dating back to the late Pleistocene. Taxonomic binning and operational taxonomic unit (OTU) prediction of the Illumina sequencing data indicated the abundance Proteobacteria (61%) followed closely by Bacterioidetes (35%). The top two most abundant genera identified, were Sphingobacterium and Acinetobacter respectively.
View Article and Find Full Text PDFSynergistic effect of mushroom extracts with standard antibiotics against pathogenic bacteria is beneficial for treating infectious diseases. The present investigation tested the antibacterial activity and synergistic effect from an edible mushroom, Calocybe indica, with standard antibiotics. The minimum inhibitory concentration (MIC) of different extracts from C.
View Article and Find Full Text PDFIn order to improve crop plants in terms of their yield, drought resistance, pest resistance, nutritional value, etc., modern agriculture has relied upon plant genetic engineering. Since the advent of recombinant DNA technology, several tools have been used for genetic transformations in plants such as Agrobacterium tumefaciens, virus-mediated gene transfer, direct gene transfer systems such as electroporation, particle gun, microinjection and chemical methods.
View Article and Find Full Text PDFThe profound advances in the biomolecular sciences over the last decades have enabled similar advances in biomedicine. These advances have increasingly challenged our abilities to deploy them in an equitable and ethically acceptable manner. As such, it has become necessary and important to teach biomedical and scientific ethics to our students who will become the researchers, medical professionals, and global citizens of the future.
View Article and Find Full Text PDFThe East Kolkata wetland, situated in West Bengal, India, is presently being exploited by housing many leather complexes surrounding the zone in and around. High amount of either untreated or partially treated liquid tannery wastes are discharged in the wetland. Treated effluent from some common effluent treatment plant (CETP) showed the presence of Cr (VI) exceeding the limiting concentration.
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