Clinical Practice Patterns in IgA Nephropathy: A Global Questionnaire-Based Survey.

Introduction: IgA nephropathy (IgAN) displays ethnic differences in disease phenotype. We aimed to examine how this common disease is managed worldwide.

Methods: An online 2-step questionnaire-based survey was conducted among nephrologists globally focusing on various management strategies used in IgAN.

Clinical Profile of Nonproteinuric Kidney Disease in Type 2 Diabetic Patients in India.

Background: Diabetic kidney disease (DKD) is the commonest cause of end-stage renal disease (ESRD) across the world. Development of microalbuminuria is the earliest marker of DKD and predicts progressive decline in estimated glomerular filtration rate (eGFR). However, recent evidence has suggested that a significant proportion of type 2 diabetic patients have chronic kidney disease (CKD) without proteinuria.

Technology and Medical Care in India: Growth of Telehealth Awareness during the COVID-19 Pandemic.

Background: COVID-19 pandemic has highlighted the importance of telemedicine in health care delivery worldwide. However, the true success of telemedicine depends on patients' acceptance, which in turn is decided by their interest in telemedicine. In this study, we aim to assess the population interest in telemedicine services across India during the COVID-19 pandemic.

Impact of anxiety and depression on disease activity and quality of life in patients with lupus nephritis.

Background Of The Study: Lupus is an autoimmune disease that affects multiple body systems and requires long-term treatment. The multisystem effect of this disease and long treatment may cause anxiety and depression in patients with lupus nephritis (LN) and ultimately deteriorate their quality of life and also affects the activity of the disease.

Aim Of The Study: This study aims to assess anxiety, depression, and quality of life in patients with LN and their relationship with disease activity.

Association of vitamin D status with disease severity and outcome in Indian patients with IgA nephropathy.

Background: Vitamin D deficiency has been examined as a risk factor for severity and progression of kidney disease due to its immunomodulatory effects. There is paucity of data about its impact in IgA nephropathy (IgAN).

Methods: In a retrospective cohort study, 25 (OH) vitamin D assay was performed in bio-banked baseline serum samples collected during kidney biopsy of 105 adult patients with primary IgAN diagnosed between 2015 and 2019.

Utility and patient acceptance of telemedicine in nephrology.

Purpose: There is an increasing burden of kidney diseases worldwide and access to specialist care is limited. Telemedicine, has been relatively less used in developing countries like India. The current study aims to assess the feasibility and acceptance of telenephrology services at our institute, a public hospital.

The International IgA Nephropathy Network Prediction Tool Underestimates Disease Progression in Indian Patients.

Introduction: International IgA nephropathy (IgAN) network (IIgANN) prediction tool was developed to predict risk of progression in IgAN. We attempted to externally validate this tool in an Indian cohort because the original study did not include Indian patients.

Methods: Adult patients with primary IgAN were stratified to low, intermediate, higher, and highest risk groups, as per the original model.

Top 100 cited articles in one year of COVID-19 research - A bibliometric analysis.

Background: Coronavirus disease (COVID-19)-related scientific publications have increased exponentially during the present pandemic but their influence on biomedical literature is not known. The characteristics of highly cited articles help us to identify important advances and their scientific impact.

Objectives: In the present study, we have identified and analyzed the top 100 most highly-cited articles of COVID-19 research published in the year 2020.

Novel Heterozygous Mutations of Congenital Thrombotic Thrombocytopenic Purpura: A Rare Case Report.

Hereditary thrombotic thrombocytopenic purpura (TTP) is a genetic condition caused by mutations in gene, leading to very low levels of ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type I domain 13) activity. It is a rare condition associated with multiple reported mutations. Here, we describe a case of hereditary TTP with a compound novel heterozygous mutation along with secondary focal segmental glomerulosclerosis.

Multi-response optimization to obtain better performance and emission level in a diesel engine fueled with water-biodiesel emulsion fuel and nanoadditive.

The present study aims to investigate the optimum condition of stationary diesel engine's operating parameters to obtain better performance and emission level, where the diesel engine is fueled with different concentrations of soybean biodiesel (SB), water, and alumina (Al) nanoadditive. Taguchi method coupled with gray relational analysis has been implemented in this study to obtain the optimum concentration of SB, water, and Al nanoparticle, and statistical analysis of variance (ANOVA) is applied to obtain the individual response of operating parameters on overall engine performance and emission level. Various concentration of SB (10%, 20%, and 30%), water (10%, 20%, and 30%), and Al nanoparticle (50 ppm, 100 ppm, and 150 ppm) are mixed with base diesel (BD) by mechanical agitation and followed by an ultra-sonication process.

Combustion, performance, and emission analysis of diesel engine fueled with water-biodiesel emulsion fuel and nanoadditive.

The present study is aimed to analyze the combustion, performance, and emission characteristics of water-emulsified soybean biodiesel fueled diesel engine with alumina nanoadditive and the results compared with conventional diesel fuel (BD). Experiments were conducted in a single-cylinder, four-stroke, variable compression ratio, and natural aspirated diesel engine with an eddy current dynamometer at a constant speed of 1500 rpm. Water-soybean biodiesel emulsion fuel was prepared using a mechanical agitator, in which the water concentration was limited to 10%, whereas soybean biodiesel (SB) and surfactant concentrations were 89% and 1% by volume respectively.

Intravenous immunoglobulin therapy for dengue capillary leak syndrome in a renal allograft recipient.

A 45-year-old man presented 4 months after ABOi renal transplantation with febrile illness and bicytopenia necessitating cessation of mycophenolate mofetil. Dengue non-structural protein 1 antigen (NS1 Ag) test was positive. Lowest total leucocyte count was 3.

Dengue fever in renal allograft recipients: Clinical course and outcome.

Background: There are annual outbreaks of dengue infection in tropical and subtropical countries. This retrospective study aimed to assess the clinical manifestation of dengue and outcome in renal transplant recipients.

Methods: Renal transplant recipients diagnosed with dengue in the nephrology department during the outbreak from August 2015 to December 2015 were included in the study.

Colovesical fistula: a rare complication after renal transplantation.

Colovesical fistula per se is a rare condition and most commonly occurs secondary to diverticular disease in normal patients. Colovesical fistula in the setting of post-renal transplantation is even rarer and very few cases have been reported in literature. Patients with autosomal-dominant polycystic kidney disease (ADPKD) are predisposed to diverticulosis and hence are at a higher risk for fistula formation.

The Prevalence of New Onset Diabetes Mellitus after Renal Transplantation in Patients with Immediate Posttransplant Hyperglycemia in a Tertiary Care Centre.

Objectives: This study aimed to determine the prevalence of immediate posttransplant hyperglycemia and new onset diabetes after renal transplantation (NODAT). It also aims at answering whether posttransplant hyperglycemia is a risk factor for future development of NODAT.

Methods: A retrospective study was conducted among patients undergoing kidney transplantation under a single surgical unit in a tertiary care hospital in the past 5 years.

Bleomycin-induced skin toxicity: is it always flagellate erythema?

Bleomycin-induced skin toxicity is a rare and unique complication. We report a 35-year-old man with nodular lymphocytic predominant Hodgkin's lymphoma, stage IVB, who was started on adriamycin, bleomycin, vinblastin and dacarbazine (ABVD) chemotherapy. He developed pruritic hyperpigmented, patchy skin lesions on the neck, back, chest and thighs after IA cycle of ABVD chemotherapy.