Publications by Arunkumar Palaniyappan

Publications by authors named "Arunkumar Palaniyappan"

Mech Ageing Dev

September 2023

Aging significantly impacts the brain due to both external factors and changes in immune cells over time.
Immunosenescence and Inflammaging contribute to increased inflammation and oxidative stress in the brain, elevating cytokine levels.
This pro-inflammatory environment causes harmful alterations in brain structure and function, ultimately impairing central and neuroendocrine processes.

- Arunkumar Palaniyappan's recent research focuses on the interplay between cytokines, reactive oxygen species, and the process of brain aging, highlighting the complexities involved in age-related changes in brain function.
- The study emphasizes the significance of immunosenescence and inflammaging, detailing how these factors contribute to elevated cytokine levels and increased oxidative stress in the aging brain.
- Findings suggest that both peripheral and central immune changes play critical roles in the progression of brain aging, indicating potential targets for intervention to mitigate age-related cognitive decline.