Researchers successfully created heterofunctional polyester dendrimers up to the third generation, incorporating 21 bromine atoms, using a divergent growth method for the first time.
They utilized direct azidation reactions to transform the bromide groups into clickable azide groups.
This allows for the attachment of therapeutic and chemical agents to various sites on the dendrimers, enhancing their potential for biomedical use through various chemical reactions.
Photodynamic therapy (PDT) is a suitable alternative to currently employed cancer treatments. However, the hydrophobicity of most photosensitizers (e.g.