Publications by authors named "Arunee Thanasarasakulpong"
Article Synopsis
- The study investigates the immunogenicity of recombinant outer membrane protein H (rOmpH) from Pasteurella multocida when purified through different methods: electroelution and affinity chromatography.
- Chickens immunized with rOmpH purified via electroelution showed significantly higher antibody responses against P. multocida and a considerable reduction in bacterial adhesion compared to other treatment groups.
- Results indicated that rOmpH purified with electroelution provided strong protective effects in chickens, while those immunized with affinity chromatography-purified rOmpH displayed little to no survival against P. multocida strains.
Recombinant outer membrane protein H (rOmpH) is a potential fowl cholera vaccine candidate. The present study was aimed at developing rOmpH formulations for intranasal administration. The rOmpH was purified and formulated with either Escherichia coli enterotoxin B (LTB) or CpG oligodeoxynucleotides (ODN) as an adjuvant.
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