Design, synthesis, and anticancer evaluation of N4-substituted thiosemicarbazones derived from ortho- and para-ethoxy-benzaldehydes.

R - C(S) - NH - N = CH - R [R = o-OCHCH & R = CHN (2-EBP), R = o-OCHCH & R = CHNO (2-EBM), R = p-OCHCH & R = CHN (4-EBP), and R = p-OCHCH & R = CHNO (4-EBM)] have been synthesized. The ligands have been verified via various spectroscopic methods such as IR, NMR, etc. Single-crystal X-ray diffraction methods were applied to identify the structure of 4-EBP.

Sclareolide as Antifungal Strategy Against : Unveiling Its Mechanisms of Action.

Cryptococcal infection commonly begins as an opportunistic infection in humans, however, this can escalate to a systemic or life-threatening form in immunocompromised individuals. Here, we aim to identify novel antifungal molecules from plants resources. Sclareolide, a phytochemical classified as a sesquiterpene lactone, was assessed against H99.

Nonylphenol polybenzoxazines-derived nitrogen-rich porous carbon (NRPC)-supported g-CN/FeO nanocomposite for efficient high-performance supercapacitor application.

In this work, a straightforward and scalable method was used to generate nitrogen-rich porous carbon (NRPC), which was then incorporated with a graphitic carbon nitride and magnetite (g-CN/FeO) nanocomposite, fabricated with FeO nanoparticles as an eco-friendly and economically viable component. The fabricated NRPC/g-CN/FeO nanocomposite was applied as an electrode in supercapacitor applications. The synthesized NRPC/g-CN/FeO nanocomposite, NRPC, g-CN, and FeO were characterized by analytical and morphological analyses.

Synthesis and characterization of fluorinated graphene oxide nanosheets derived from Lissachatina fulica snail mucus and their biomedical applications.

The modern nanomedicine incorporates the multimodal treatments into a single formulation, offering innovative cancer therapy options. Nanosheets function as carriers, altering the solubility, biodistribution, and effectiveness of medicinal compounds, resulting in more efficient cancer treatments and reduced side effects. The non-toxic nature of fluorinated graphene oxide (FGO) nanosheets and their potential applications in medication delivery, medical diagnostics, and biomedicine distinguish them from others.

Multifaceted exploration of acylthiourea compounds: In vitro cytotoxicity, DFT calculations, molecular docking and dynamics simulation studies.

This study reports the synthesis and analysis of biologically active acylthiourea compounds (1 and 2) with a cyclohexyl moiety. The compounds were characterized using UV-Visible, FT-IR, H/C NMR, and elemental analysis. The crystal structure of 2 was solved, revealing intra- and inter-molecular hydrogen bonds.

Synthesis and characterization of marine seagrass (Cymodocea serrulata) mediated titanium dioxide nanoparticles for antibacterial, antibiofilm and antioxidant properties.

Cymodocea serrulata mediated titanium dioxide nanoparticles (TiO NPs) were successfully synthesized. The XRD pattern and FTIR spectra demonstrated the crystalline structure of TiO NPs and the presence of phenols, flavonoids and alkaloids in the extract. Further SEM revealed that TiO NPs has uniform structure and spherical in shape with their size ranged from 58 to 117 nm.

Anti-quorum Sensing and Anti-biofilm Effect of Nocardiopsis synnemataformans RMN 4 (MN061002) Compound 2,6-Di-tert-butyl, 1,4-Benzoquinone Against Biofilm-Producing Bacteria.

In this study, the anti-biofilm compound of 2,6-Di-tert-butyl, 1,4-benzoquinone was purified from Nocardiopsis synnemataformans (N. synnemataformans) RMN 4 (MN061002). To confirm the compound, various spectroscopy analyses were done including ultraviolet (UV) spectrometer, Fourier transform infrared spectroscopy (FTIR), analytical high-performance liquid chromatography (HPLC), preparative HPLC, gas chromatography-mass spectroscopy (GC-MS), liquid chromatography-mass spectroscopy (LC-MS), and 2D nuclear magnetic resonance (NMR).

Direct Synthesis of cubic shaped AgS on Ni mesh as Binder-free Electrodes for Energy Storage Applications.

A facile approach of chemical bath deposition was proposed to fabricate direct synthesis of silver sulphide (AgS) on nickel (Ni) mesh without involvement for binders for supercapacitor electrodes. The phase purity, structure, composition, morphology, microstructure of the as-fabricated AgS electrode was validated from its corresponding comprehensive characterization tools. The electrochemical characteristics of the AgS electrodes were evaluated by recording the electrochemical measurements such as cyclic voltammetry and charge/discharge profile in a three electrode configuration system.