Enhanced Photocatalytic Degradation of Reactive Dyes Under Visible Light Using ZnO/CdS/Co Nanocomposites: A Step Toward Advanced Environmental Remediation.

In this study, ZnO, CdS, ZnO/CdS, and ZnO/CdS/Co nanostructures were successfully synthesized using a simple chemical precipitation method. The formation of these nanostructures was confirmed through x-ray diffraction (XRD), but their morphological properties were analyzed using scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Their optical properties were investigated using UV-visible diffuse reflectance spectroscopy (UV-DRS) and photoluminescence spectroscopy (PL).

Catheter-Based Fontan Completion Without Prior Surgical Preparation: Is This the Way Forward?

We report 3 cases of transcatheter Fontan completion in conventional Glenn anastomosis patients without surgical preparation by creating a tunnel between the pulmonary artery and right atrium. Cavocaval anastomosis is established by placing a covered stent graft within the scaffold created with the uncovered stents at the pulmonary artery-right atrium and inferior vena cava-right atrium junction.

Antibacterial efficacy of carnosic acid as an intracanal medicament against : Quantitative polymerase chain reaction study.

Aim: The aim of this study was to quantitatively assess the antibacterial effectiveness of carnosic acid, propolis, and calcium hydroxide when used as intracanal medications against .

Methodology: Forty-six human mandibular single-rooted premolar root lengths were standardized to 12 mm after decoronation. Cleaning and shaping were performed.

Journey tracker: driver alerting system with a deep learning approach.

Negligence of public transport drivers due to drowsiness poses risks not only to their own lives but also to the lives of passengers. The designed journey tracker system alerts the drivers and activates potential penalties. A custom EfficientNet model architecture, based on EfficientNet design principles, is built and trained using the Media Research Lab (MRL) eye dataset.

Development and validation of the chemotherapy adherence assessment scale (CAAS).

Background: Adherence to chemotherapy regimens is crucial for achieving optimal treatment outcomes in cancer patients. However, measuring adherence remains a significant challenge. This study aimed to develop and validate a comprehensive self-report tool for assessing chemotherapy adherence.

Prevalence and correlates of depression, anxiety, and stress among adolescents in urban and rural areas of Mysuru, South India.

Background: Adolescence, a volatile period of growth between the ages of 10 and 19, is associated with increased vulnerability to mental health problems. Factors such as academic pressure can contribute to these challenges.

Objectives: The current study aimed to evaluate the factors and prevalence of depression, anxiety, and stress among adolescents in the urban and rural areas of Mysuru district.

Orthogonal analysis reveals inconsistencies in cargo loading of extracellular vesicles.

Since extracellular vesicles (EVs) have emerged as a promising drug delivery system, diverse methods have been used to load them with active pharmaceutical ingredients (API) in preclinical and clinical studies. However, there is yet to be an engineered EV formulation approved for human use, a barrier driven in part by the intrinsic heterogeneity of EVs. API loading is rarely assessed in the context of single vesicle measurements of physicochemical properties but is likely administered in a heterogeneous fashion to the detriment of a consistent product.

Exploring okra-derived compounds as prospective aromatase inhibitors: a computational study for enhanced breast cancer therapy.

Estrogen receptor-positive breast cancer represents itself as the most prevalent malignancy among postmenopausal women. One of the promising therapeutic approaches involves the use of Aromatase inhibitors, which competitively bind to Aromatase, reducing estrone and estradiol levels. While current drugs have improved survival rates, they are not without adverse effects.

Plasma-derived Extracellular Vesicles (EVs) as Biomarkers of Sepsis in Burn Patients via Label-free Raman Spectroscopy.

Sepsis following burn trauma is a global complication with high mortality, with ~60% of burn patient deaths resulting from infectious complications. Sepsis diagnosis is complicated by confounding clinical manifestations of the burn injury, and current biomarkers markers lack the sensitivity and specificity required for prompt treatment. Circulating extracellular vesicles (EVs) from patient liquid biopsy as biomarkers of sepsis due to their release by pathogens from bacterial biofilms and roles in subsequent immune response.

Extracellular Vesicles from Highly Metastatic Osteosarcoma Cells Induce Pro-Tumorigenic Macrophage Phenotypes.

Metastasis is the principal factor in poor prognosis for individuals with osteosarcoma (OS). Understanding the events that lead to metastasis is critical to develop better interventions for this disease. Alveolar macrophages are potentially involved in priming the lung microenvironment for OS metastasis, yet the mechanisms involved in this process remain unclear.

Central Retinal Artery Occlusion in Young Adults at High Altitude: Thin Air, High Stakes.

Rana, Vipin, Pradeep Kumar, Sandeepan Bandopadhyay, Vijay K. Sharma, Meenu Dangi, Dattakiran Joshi, Sanjay Kumar Mishra, Satyabrat Srikumar, and V.A.

Influence of maxillary first molar rotation on the severity of dental class II malocclusion: A cross-sectional study.

Aim: The aim of the study was to evaluate and assess the influence of maxillary molar rotation on severity of dental class II malocclusion.

Materials And Methods: The study comprised of 4 different groups namely, 1/4th class II malocclusion, 2/4th class II malocclusion, 3/4th class II malocclusion and full class II malocclusion involving sample size of 20,15,16 and 12. The samples were subjected to digital evaluation of maxillary 1st permanent molar rotation using 4 parameters namely angle of Friel, Ricketts E-Line, angle of Henry and Premolar angle.

Application of artificial intelligence to corelate food formulations to disease risk prediction: a comprehensive review.

Clinicians and administrators are applying Artificial Intelligence (AI) Techniques widely as the promising results of their applications in the healthcare have been established. The meaningful impact of the AI applications will be limited unless it is coherently applied with human diagnosis and inputs from specialist clinician. This will help to address limitations and take advantage of the promises of the AI techniques.

Development and validation of a comprehensive needs assessment tool to assess the burden of cancer chemotherapy patients attending a tertiary care hospital.

Introduction: In India in 2020, there were an estimated 1.39 million cancers present in the country. Chemotherapy patients experience several problems such as ADRs (adverse drug reactions), and because of this, many dropouts have been happening.

Successful management of Methemoglobinemia and G6PD deficiency in a patient posted for surgical excision of branchial cyst.

A 27-year-old female patient who came for branchial cyst excision was found to have cyanosis and a saturation gap during preanesthetic check-up and hence she was referred to haematology for further workup. She had a Hb of 9 gm% with all other baseline tests as normal. Blood samples were sent for methaemoglobin estimation and related work up to the National Institute of Immunohematology (NIIH) Mumbai.

Isolation, cloning, and functional analysis of a putative constitutive promoter of E3 ubiquitin-protein ligase RF4 from Coleus amboinicus Lour.

A promoter is a region in the genome sequence located upstream of the transcription start site comprising cis acting elements that initiates and regulates the transcription of an associated genes and restriction endonucleases. As the need for genetically engineered plants has widened, the requirement to develop methods to optimize the control of transgene expression has also increased. Therefore, analyzing the functionality of the promoter is very important in understanding the target gene expression.

Heavy metals in coral reef sediments of Kavaratti Island, India: An integrated quality assessment using GIS and pollution indicators.

The present study aims to document the contamination levels and ecological risks of heavy metals in the sediments of Kavaratti lagoon, India. A total of 15 sediment samples were collected for the analysis of Al, Pb, Cd, Cu, Cr, Mn, Ni and Zn. The decreasing trend of heavy metals was observed in the lagoon sediment as Pb > Zn > Al > Mn > Ni > Cr > Cd > Cu.

An efficient optical properties of Sn doped ZnO/CdS based solar light driven nanocomposites for enhanced photocatalytic degradation applications.

Metal sulfide - semiconductor nanocomposites synthesized with well-defined tin metal, exhibited the wide bandgap, the absorptions are limited to the UV-vis region for reduction of Reactive Blue 160 (RB 160) under solar light irradiation. The prepared samples were characterized using optoelectronic techniques. Conveniently, a wider range of wavelengths and physical properties can be enabled by doping these metal oxide nanoparticles.

Volatile Organic Compounds as Potential Biomarkers for Noninvasive Disease Detection by Nanosensors: A Comprehensive Review.

Biomarkers are biological molecules associated with physiological changes of the body and aids in the detecting the onset of disease in patients. There is an urgent need for self-monitoring and early detection of cardiovascular and other health complications. Several blood-based biomarkers have been well established in diagnosis and monitoring the onset of diseases.

Beyond lipids: Novel mechanisms for parenteral nutrition-associated liver disease.

Parenteral nutrition (PN) is a therapy that delivers essential nutrients intravenously to patients who are unable to meet their nutrition requirements via standard enteral feeding. This methodology is often referred to as PN when accompanied by minimal or no enteral nutrition (EN). Although PN is lifesaving, significant complications can arise, such as intestinal failure-associated liver disease and gut-mucosal atrophy.

Heavy metal impression in surface sediments and factors governing the fate of macrobenthic communties in tropical estuarine ecosystem, India.

The present study aims to investigate the contamination of heavy metals in the sediments of a tropical ecosystem, India, and to evaluate the factors responsible for the dominance of specific macrobenthic communities, particularly in estuarine sediments. For the analysis of Cu, Cr, Ni, Zn, Pb and Cd in sediments, acid digestion and subsequent quantification by microwave plasma atomic emission spectroscopy was performed, whereas for Hg determination, cold vapour atomic absorption spectrophotometry was used. The general trend of the heavy metal concentration was observed as Cr > Cu > Zn > Ni > Pb > Cd > Hg, regardless of any seasonal alteration.

Primary chest wall Burkitt lymphoma in a case of HIV infection with immune reconstitution.

Burkitt lymphoma (BL) develops at an increased frequency in patients with HIV irrespective of the CD4 count. Lymph nodes and gastrointestinal tract are common sites of involvement by BL; however, primary chest wall BL is rare. A 52-year-old man on highly active antiretroviral therapy (HAART) for HIV with a CD4 count of 0.

Validation of EURO-D, a geriatric depression scale in South India: Findings from the Mysore study of Natal effects on Ageing and Health (MYNAH).

Introduction: Many of the assessment tools used to study depression amongst older people in low- and middle- income countries (LMICs) are adaptations of instruments developed in other cultural settings. There is a need to validate those instruments in LMICs.

Methods: 721 men and women aged 55-80 years from the Mysore Birth Records Cohort underwent standardised assessments for sociodemographic characteristics, cardiometabolic risk factors, cognitive function and mental health.

SARS-CoV-2 spike protein: Site-specific breakpoints for the development of COVID-19 vaccines.

SARS-CoV2 is a member of human coronaviruses and is the causative agent of the present pandemic COVID-19 virus. In order to control COVID-19, studies on viral structure and mechanism of infectivity and pathogenicity are sorely needed. The spike (S) protein is comprised of S1 & S2 subunits.