Objective: This paper introduces , a novel web-based healthcare system designed to enable healthcare professionals to monitor patients remotely with enhanced efficacy. Central to our system is its integration with the Vitaliti™ wearable, equipped with biosensors for real-time vital signs monitoring. distinguishes itself by offering advanced, custom visualizations for interactive engagement with medical data, facilitating rapid clinical decision-making through intuitive access to vital signs and trends.
View Article and Find Full Text PDFIntroduction: Hand injuries, particularly those involving the fingers, are complex and often necessitate meticulous surgical interventions. Cross-finger flaps (CFFs) are a reliable technique for covering finger defects, with the choice of skin graft at the donor site playing a crucial role in the procedure's success. Split-thickness skin grafts (STSGs) and full-thickness skin grafts (FTSGs) are commonly used, each offering distinct advantages and drawbacks.
View Article and Find Full Text PDFAtten Percept Psychophys
November 2024
When a spiky object is occluded, we expect its spiky features to continue behind the occluder. Although many real-world objects contain complex features, it is unclear how more complex features are amodally completed and whether this process is automatic. To investigate this issue, we created pairs of displays with identical contour edges up to the point of occlusion, but with occluded portions exchanged.
View Article and Find Full Text PDFIntroduction: Post-operative pain after orthopedic surgery has remained a challenging problem, which prolongs hospital stay and early rehabilitation. Pregabalin comes under the class of gabapentinoids that have been used in postoperative pain in arthroplasty and spine surgeries but studies regarding its role as pre-emptive analgesia in orthopedic limb surgeries are very few.
Aims: To compare the efficacy of pre-operative pregabalin with a placebo drug in early post-operative pain management for lower limb orthopedics surgeries.
Objectives: To compare the incidence of central line associated blood stream infections (CLABSI) with the use of umbilical venous catheters (UVC) or peripherally inserted central cathethers (PICC) as primary vascular access in preterm neonates.
Method: This was an open-label, two parallel-arm, randomized controlled trial which included hospitalized neonates with birth weight <1250g who required a central venous access on day 1 of life. The neonates were randomized to either UVC or PICC groups and evaluated for the incidence of CLABSI.
Background: This study delves into newborn care and infant-feeding practices in rural Odisha, specifically focusing on the rural KBK + region of Odisha (Kalahandi-Bolangir-Koraput region), inhabited predominantly by Schedule Tribes and Schedule Castes individuals. There has been an improvement in the health indicators in these areas in recent times. In the background of improved health indicators in these areas, this research explores the current and changing newborn care practices and attempts to gain insight into people's perceptions of the factors that brought about the changes.
View Article and Find Full Text PDFA novel and efficient fragment-based assembly of symmetrical -peptidotraizoles has been developed based on double Sharpless azide-alkyne click chemistry. A new Cu(II) catalyzed protocol with a wide substrate scope was developed for accessing the symmetrical alkylidene azidoamide fragment that yields the products in very good yields at room temperature without employing column purifications. The propargylated β-acetamido ketone fragment was accessed using another Cu(II) catalyzed room temperature MCR protocol.
View Article and Find Full Text PDFBackground: Robotic-assisted total knee replacement (RA-TKR) is a significant advancement in orthopedic surgery, but intra-operative decision-making remains challenging. Pre-operative imaging techniques, particularly CT scans, have gained momentum, providing insights into the patient's anatomy, improving implant positioning and alignment. However, further research is needed to explore their influence on RA-TKR planning and execution.
View Article and Find Full Text PDFA category of cytoplasmic transcription factors called STATs mediates intracellular signaling, which is frequently generated at receptors on cell surfaces and subsequently sent to the nucleus. STAT3 is a member of a responsible for a variety of human tumor forms, including lymphomas, hematological malignancies, leukemias, multiple myeloma and several solid tumor types. Numerous investigations have demonstrated constitutive STAT3 activation lead to cancer development such as breast, head and neck, lung, colorectal, ovarian, gastric, hepatocellular, and prostate cancers.
View Article and Find Full Text PDFObjectives: This study evaluated the occupational injuries and health hazards associated with fishing as an occupation among non-traditional rural tribal fishing communities in the coastal region of Tamil Nadu, India.
Methods: This cross-sectional study included a total of 170 individuals belonging to a fishing community, comprising both male ( = 82) and female ( = 88) participants. The demographic details including occupational history, lifestyle characteristics, socio-economic status, personal habits, and health status were assessed through the questionnaire survey.
Purpose: The purpose is to report financial loss, demographic metrics, and mechanisms of injury associated with eye injuries in the National Basketball Association (NBA) from the 2010-2011 to 2017-2018 seasons.
Methods: We performed a retrospective review of eye injuries in the NBA from the 2010-2011 to 2017-2018 seasons using publicly available information from Basketball Reference and the Pro Sports Transactions websites. Only injuries of the eye and adnexa that caused players to miss games in the regular season and playoffs were included in the study.
Objective: To estimate the association of patient-related demographic, socioeconomic status, physical activity, stress, and dietary factors influencing the relationship between salivary and blood glucose levels in individuals with and without diabetes mellitus (DM).
Method: This cross-sectional study was conducted on 166 participants with and without DM. Saliva and blood were collected to estimate the glucose levels.
J Stomatol Oral Maxillofac Surg
April 2024
Purpose: Various medications are administered to treat Coronavirus Disease 2019 (COVID-19) infection and prevent its complications. Some medicines have complications and long-term effects, which may mimic other conditions, making precise diagnosis difficult. This report aims to bring to light one such complication, medication-related osteonecrosis of the jaw (MRONJ), secondary to a commonly prescribed medication for preventing lung fibrosis post-COVID-19 infection.
View Article and Find Full Text PDFIn search of the cause behind the similarities often seen in the fragmentation of PANHs, vacuum ultraviolet (VUV) photodissociation of two pairs of isomers quinoline-isoquinoline and 2-naphthylamine-3-methyl-quinoline are studied using the velocity map imaging technique. The internal energy dependence of all primary fragmentation channels is obtained for all four target molecules. The decay dynamics of the four molecules is studied by comparing their various experimental signatures.
View Article and Find Full Text PDFThe growing concerns surrounding water supply, driven by factors such as population growth and industrialization, have highlighted the need for accurate estimation of streamflow at the river basin level. To achieve this, rainfall-runoff models are widely employed as valuable tools in watershed management. For this specific study, two modelling approaches were employed: the Soil and Water Assessment Tool (SWAT) model and a set of eight artificial intelligence (AI) models.
View Article and Find Full Text PDFJ Maxillofac Oral Surg
September 2023
Introduction: With little evidence available in the literature, this study tries to clinically determine the efficiency and outcomes of non-surgical management of post-traumatic Zygomaticomaxillary complex (ZMC) fractures.
Materials And Methods: One hundred and three patients with post-traumatic isolated ZMC fractures managed conservatively for various reasons were identified. The patients were classified based on the Zingg et al.
Background: Post traumatic seizures (PTS) and post traumatic epilepsy (PTE) are potential consequences of traumatic brain injury (TBI). There is no consensus regarding its management among treating doctors.
Purpose: We have undertaken a global survey to assess the variability of management practices of PTS and PTE and highlight the pressing need to formulate uniform practice guidelines.
Coronavirus disease 2019 (COVID-19) is characterized by a pro-inflammatory state associated with organ failure, thrombosis, and death. We investigated a novel inflammatory biomarker, γ' fibrinogen (GPF), in 103 hospitalized patients with COVID-19 and 19 healthy controls. We found significant associations between GPF levels and the severity of COVID-19 as judged by blood oxygen saturation (SpO).
View Article and Find Full Text PDFNuclear envelope (NE) assembly defects cause chromosome fragmentation, cancer, and aging. However, major questions about the mechanism of NE assembly and its relationship to nuclear pathology are unresolved. In particular, how cells efficiently assemble the NE starting from vastly different, cell type-specific endoplasmic reticulum (ER) morphologies is unclear.
View Article and Find Full Text PDFBackground Prophylactic antifungals are often used in high-risk babies in neonatal intensive care units (NICUs) to reduce invasive fungal infections (IFIs). However, existing guidelines regarding prophylactic antifungal usage do not clearly define the high-risk population. This study aimed to assess the practices related to prophylactic antifungal use in NICUs in India.
View Article and Find Full Text PDFSensing acetylcholine has been predominantly based on enzymatic strategies using acetylcholine esterase and choline oxidase because of its electrochemical inertness. Electrified liquid-liquid interfaces are not limited to oxidation/reduction processes, and can be utilized to detect non-redox molecules which cannot be detected using conventional solid electrodes. In this study, a disposable micropipette tip based liquid-organogel interface, in the presence/absence of calixarene has been developed as a platform for sensing acetylcholine.
View Article and Find Full Text PDFAtten Percept Psychophys
April 2024
Humans robustly associate spiky shapes to words like "Kiki" and round shapes to words like "Bouba." According to a popular explanation, this is because the mouth assumes an angular shape while speaking "Kiki" and a rounded shape for "Bouba." Alternatively, this effect could reflect more general associations between shape and sound that are not specific to mouth shape or articulatory properties of speech.
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