Synopsis of recent research by authors named "Arun Mahesh"
- Arun Mahesh's recent research focuses on the complex gene regulatory landscapes involved in neurodevelopmental processes and cancer, specifically investigating mechanisms underlying cerebral cortex folding and chemotherapy resistance in triple-negative breast cancer (TNBC).
- His studies have uncovered specific subpopulations of cells that contribute to chemoresistance in TNBC patients, as well as biomarkers that may aid in therapy response and identify potential therapeutic targets.
- Additionally, Mahesh's work emphasizes the role of epigenetic and transcriptional regulatory mechanisms in both brain development and cancer metastasis, contributing to a greater understanding of cellular behavior influenced by gene expression.
