Publications by authors named "Arun Kumar Viswanadha"

Introduction: Knowledge translation from research to clinical practice can often be challenging, and practice modification patterns among surgeons may stem from a variety of sources, including personal experience, peer influence, ongoing education, and evolving research findings.

Research Question: This study aimed to investigate the adoption patterns amongst surgeons for newer innovations and to analyse the factors affecting the implementation of the same in clinical practice. We used the adoption of osteobiologics as a case example.

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Study Design: Cross-sectional study.

Objectives: To assess global practices and preferences in the use of osteobiologics for anterior cervical discectomy and fusion (ACDF) and identify factors influencing the choice of specific osteobiologics.

Methods: An online survey developed by AO Spine was distributed to spine surgeons worldwide.

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Study Design: Systematic literature review.

Objectives: To analyze the evidence available reporting complications in single or two-level anterior cervical discectomy and fusion (ACDF) using a demineralized bone matrix (DBM), hydroxyapatite (HA), or beta-tricalcium phosphate (β-TCP).

Methods: A systematic review of the literature using PubMed, EMBASE, Cochrane Library, and ClinicalTrials.

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Study Design: Systematic Review of the Literature.

Objective: The purpose of this study was to perform a systematic review describing fusion rates for anterior cervical discectomy and fusion (ACDF) using autograft vs various interbody devices augmented with different osteobiologic materials.

Methods: A systematic review limited to the English language was performed in Medline, Embase and Cochrane library using Medical Subject Heading (MeSH) terms.

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Study Design: Guideline.

Objectives: To develop an international guideline (AOGO) about the use of osteobiologics in anterior cervical discectomy and fusion (ACDF) for treating degenerative spine conditions.

Methods: The guideline development process was guided by AO Spine Knowledge Forum Degenerative (KF Degen) and followed the Guideline International Network McMaster Guideline Development Checklist.

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Article Synopsis
  • The study is a randomized control trial that evaluates the safety and effectiveness of tranexamic acid (TXA) in reducing blood loss during instrumented spine surgeries.
  • A total of 104 patients were divided into four groups: intravenous (ivTXA), local infiltration (loTXA), topical application (tTXA), and a control group, with various outcomes measured, including blood loss and need for transfusions.
  • Results showed that all TXA methods effectively reduced blood loss, with tTXA having the best outcomes for postoperative blood conservation, indicating that local infiltration of TXA is a viable method for minimizing blood loss in these surgeries.
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Study Design: Observational study.

Purpose: The purpose of this study is to analyze the surgeon's neck postures while performing lumbar spinal surgeries.

Overview Of Literature: Lumbar spinal surgeries are on rising trend, and with increase in number of procedures, the average time spent by a spine surgeon performing surgical procedures is also increasing.

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Study Design: Prospective cohort study.

Objective: To analyze the serum and drain concentrations of antibiotics administered by two different routes and compare the results.

Summary Of Background Data: Systemic antibiotics are expected to reach the surgical site and maintain adequate concentrations of the drug to prevent infection.

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Article Synopsis
  • This literature review examines clinical factors and comorbidities, beyond just radiological parameters, that influence the management of adult spinal deformity (ASD).
  • ASD involves several complications, including spinal deformity, stenosis, and various comorbidities, which lead to differing patient management strategies.
  • The review analyzed 614 citations, ultimately selecting 11 studies, and found that leg pain, spinal stenosis, obesity, osteoporosis, smoking, and age significantly impact surgical outcomes and highlight the need for better classifications of ASD patients.
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