Publications by authors named "Arun K Shettar"
The present study was aimed to synthesize the silver nanoparticles from Wang. and evaluating its biomedical applications. The leaves of collected and subjected for the standard procedure of Soxhlet extraction using distilled water as a solvent.
View Article and Find Full Text PDFThe present work focuses on the synthesis of novel heterocycles 2-(aryloxy)-3-(4,5-diaryl-1H-imidazol-2-yl)quinolines (6k-v) by an effective condensation reaction. These molecules exhibited fluorescent properties and hence for the proper understanding of their optical behavior and quantum yields, solvatochromic studies have been carried out. Further, frontier molecular orbitals, molecular electrostatic potential (MEP), and geometrical structure optimization have been investigated using the BLYP/6-311G ++ (d, p) method.
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- - The study investigated the wound healing effects of bark ethanolic extract (MZE) using various models, including animal tests with Wistar albino rats, comparing MZE with a control and a povidone-iodine treatment.
- - Results showed that MZE significantly enhanced wound contraction (99.88% after 20 days) and fast-tracked epithelization compared to untreated rats, indicating its potential as an effective treatment.
- - Additionally, MZE treatment increased mechanical strength and boosted levels of proteins related to healing, revealing its capability to promote cell migration and improve skin tissue regeneration.
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- The study presents a method to create a chitosan-silver nanocomposite (CS-Ag NC) using kiwi fruit juice, which serves as a natural reducing agent.
- Various characterization techniques confirmed the structure and properties of the CS-Ag NC, which was then employed as a catalyst to convert 4-nitrophenol into 4-aminophenol.
- The nanocomposite demonstrated significant cytotoxic effects against various cancer cell lines and showed promising wound healing properties, with a high percentage of wound closure comparable to a standard drug.
Natural extract-based bio-composite material for wound healing is gaining much attention due to risk of infection and high cost of commercial wound dressing film causes serious problem on the human well-being. Herein, the study outlines the preparation of Poly (vinyl alcohol)/Chitosan/Basella alba stem extract (BAE) based bio-composite film through solvent casting technique and well characterized for wound healing application. Incorporation of BAE into Poly (vinyl alcohol)/Chitosan matrix has shown existence of secondary interactions confirmed by FT-IR analysis.
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- Thiazolidinedione (TZD) drugs improve insulin sensitivity and manage blood sugar levels in type 2 diabetes patients.
- A new series of compounds called coumarin-4-yl-1,2,3-triazol-4-yl-methyl-thiazolidine-2,4-diones (TZD1-TZD18) were created using "Click Chemistry" and tested for their effectiveness in glucose uptake and toxicity against human kidney cells.
- The study found that the compounds TZD4, TZD10, TZD14, and TZD16 were particularly effective in lowering blood glucose levels, outperforming the standard medication, Pioglitazone.
Silver nanoparticles (AgNPs) have recently gained interest in the medical field because of their biological features. The present study aimed at screening secondary metabolites, quantifying their flavonoids and total phenolics content, green synthesis and characterization of silver nanoparticles. In addition, an assessment of in vitro cytotoxic, antioxidant, anti-inflammatory and wound healing activity of and its synthesized AgNPs was carried out.
View Article and Find Full Text PDFThe cold extraction method was used to obtain the aqueous extract of leaves in a ratio of 1:10. Iron nanoparticles (FeNPs) were synthesized using aqueous leaf extract of as a reducing agent. The phytoreducing approach was used to make FeNPs by mixing 1 mL of plant extract with 1 mM of ferric sulfate.
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