Publications by authors named "Arun K Mahapatra"

Introduction: Febrile neutropenia (FN) episodes in sarcoma patients may be due to potentially life-threatening microbiologically defined infection (MDI). Clinical decision rules (CDRs) such as the Australian-UK-Swiss (AUS) rule have been developed to risk-stratify FN episodes, allowing for early discharge of patients at low risk of MDI. The AUS rule was validated in the multicentre Predicting Infectious Complications in Children with Cancer (PICNICC) FN episode dataset.

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Prostate cancer (PC) is among the most prevalent cancers in males. It is the leading cause of death in men, in around 48 out of 185 countries. Increased androgen receptor (AR) activity is the key factor contributing to the development or progression of newly diagnosed cases of prostate cancer.

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Ayurveda has unique and relevant methods in nosology, symptomatology, and drug selection. These methods need a novel and effective way of presentation for convenient comprehension and implementation. 'Clinical algorithms' is one such way, wherein a large amount of data is simplified, conceptual intricacies abstracted, and clinical application made easier.

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Article Synopsis
  • - Breast cancer is the leading cause of cancer-related deaths among women globally, with ongoing issues like drug resistance and metastasis despite treatment advancements.
  • - The study investigates the potential of five natural compounds in a herbal formulation called Krishnadi Churna to target specific genes involved in breast cancer, using network pharmacology to identify and assess these interactions.
  • - Key genes linked to breast cancer progression were found to be frequently mutated in patients, and the herbal compounds showed promising binding affinity, indicating their potential as new treatment options for breast cancer.
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Methicillin-resistant Staphylococcus aureus (MRSA) is a life-threatening superbug causing infectious diseases such as pneumonia, endocarditis, osteomyelitis, etc. Conventional antibiotics are ineffective against MRSA infections due to their resistance mechanism against the antibiotics. The Penicillin Binding Protein (PBP2a) inhibits the activity of antibiotics by hydrolyzing the β-lactam ring.

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Objective: The world continues to face the COVID-19 crisis, and efforts are underway to integrate traditional medicine interventions for its effective management. The study aimed to determine the efficacy of the "AYURAKSHA" kit in terms of post-interventional percentage of COVID-19 IgG positivity, immunity levels, and quality of life (QoL) against COVID-19.

Method: This was a non-randomized controlled, prospective intervention trial, done after the distribution of 80,000 AYURAKSHA kits (constituent of Sanshamani Vati, AYUSH Kadha, and Anu Taila) among Delhi police participants in India.

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Background: AIAPGET 2019, an all India ranking entrance Test for MD/MS courses of Ayurveda, Unani, Siddha and Homeopathy stream was conducted by joint collaboration of National Testing Agency (NTA) and All India Institute of Ayurveda (AIIA). In this article, we present the item analysis of AIAPGET 2019 Ayurveda stream MCQs.

Objectives: The aim of this article was to analyse the MCQs of AIAPGET 2019 of Ayurveda stream.

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