Int J Neuropsychopharmacol
January 2022
From the earliest days of the coronavirus disease 2019 (COVID-19) pandemic, there have been reports of significant neurological and psychological symptoms following Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection. This narrative review is designed to examine the potential psychoneuroendocrine pathogenic mechanisms by which SARS-CoV-2 elicits psychiatric sequelae as well as to posit potential pharmacologic strategies to address and reverse these pathologies. Following a brief overview of neurological and psychological sequelae from previous viral pandemics, we address mechanisms by which SARS-CoV-2 could enter or otherwise elicit changes in the CNS.
View Article and Find Full Text PDFBackground: Breast cancer is the most common cancer diagnosed among women and is the second leading cause of cancer death. Homeopathic medicines are part of the alternative medicines that are given as a supportive therapy in breast cancer. The objective of this study was to investigate the anticancer activity of commercially available homeopathic preparations of Terminalia chebula (TC) and evaluate their nanoparticulate nature.
View Article and Find Full Text PDFObjectives The social positioning (i.e. social status and autonomy) of women in the household facilitates women's access to and decision-making power related to family planning (FP).
View Article and Find Full Text PDFObjective: To assess whether intimate partner violence (IPV) is associated with discordant reports of contraceptive use (whereby wives but not husbands report such use) among married couples in Maharashtra, India.
Methods: The present cross-sectional study in rural Maharashtra, India, analyzed survey data collected in 2012 among husbands and wives aged 18-30 years, fluent in Marathi, with no prior sterilization, and with no current pregnancy or plans to conceive. Crude and adjusted logistic regression models assessed husbands' perpetration of IPV in relation to discordant reports of contraceptive use.
Objective: Evidence has linked economic hardship with increased intimate partner violence (IPV) perpetration among males. However, less is known about how economic debt or gender norms related to men's roles in relationships or the household, which often underlie IPV perpetration, intersect in or may explain these associations. We assessed the intersection of economic debt, attitudes toward gender norms, and IPV perpetration among married men in India.
View Article and Find Full Text PDFBackground: Diabetes mellitus is a common endocrine disorder characterized by hyperglycemia eventually resulting in long-term complications. Increased glycation of proteins is implicated in the pathogenesis of complications. For treatment of diabetes, Syzygium jambolanum and Cephalandra indica are frequently prescribed in homeopathy.
View Article and Find Full Text PDFEnvironmental lead exposure has been linked to learning and memory impairments as well as psychosocial deficits in children. Although the precise mechanisms by which lead exerts these effects are not completely understood, experimental animal studies suggest the involvement of mesolimbic dopamine system. Here, we investigated the effects of post weaning, 90-day exposure to 50ppm lead on the responsiveness of extracellular dopamine in the nucleus accumbens core to quinpirole and eticlopride using in vivo microdialysis in anesthetized Long-Evans rats.
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