Publications by authors named "Arun Govind G"
Efficient purification of Apolipoprotein A1 (ApoA1) from plasma by HEA HyperCel™: An alternative approach.
Arun Govind G Agamudi Shivasankaran Kamalanathan Mookambeswaran Arunachalam Vijayalakshmi Krishnan Venkataraman
J Chromatogr B Analyt Technol Biomed Life Sci
January 2018
Article Synopsis
- HDL-ApoA1 is crucial for preventing atherosclerosis and heart diseases, but purifying it from blood plasma has been complicated and inefficient in the past.
- A new two-step purification method was developed, utilizing ammonium sulfate precipitation followed by HEA HyperCel™ chromatography, which significantly improved the process.
- The method resulted in a 63% yield of pure, monomeric ApoA1, making it a promising alternative for further biochemical and clinical research.