Gemini Surfactant-Induced Cysteine-Capped Copper Nanoclusters Self-Assembly with Enhanced Peroxidase-Like Activity and Colorimetric Glutathione Sensing.

We have prepared a novel assembly with copper nanoclusters (CuNCs) and imidazolium-based gemini surfactants (different chain lengths). These novel mimic enzymes formed through the assembly of nanocluster-gemini surfactants have been utilized in creating colorimetric sensors to detect biomolecules. Yet, understanding the method for detecting glutathione (GSH) and its sensing mechanism using this specific assembly-based colorimetric sensor poses a significant challenge.

Study of the self-assembly of a gemini surfactant induced by anionic QDs in aqueous solution.

The interaction of anionic quantum dots (QDs) with a gemini surfactant (1,1'-(propane-1,3-diyl-2-ol)bis(3-hexadecyl-1-imidazol-3-ium)) bromide [CIm-3OH-ImC]Br in water has been investigated, yielding a unique class of luminescent self-assemblies. Instead of engaging with the QDs directly, the dimeric surfactant self-associates into micelles first. After adding [CIm-3OH-ImC]Br to aqueous solutions containing QDs, two types of structural formations, supramolecular and vesicles, were confirmed.