Noninvasive evaluation of splanchnic tissue oxygenation using near-infrared spectroscopy in preterm neonates.

Background: Diagnosis of necrotizing enterocolitis (NEC) in preterm neonates is challenging. We hypothesized that regional splanchnic oxygen saturation (rsSO₂) measured by near-infrared spectroscopy (NIRS) is a biomarker for mesenteric perfusion.

Objective: To evaluate feasibility and safety of continuous rsSO₂ monitoring in preterm infants in the first 14 days of life.