Publications by authors named "Arum R Yoon"
Article Synopsis
- TWIST1 is a key transcription factor involved in prostate cancer metastasis and is reactivated in tumors, suggesting its role in survival.
- The study shows TWIST1 interacts with WDR5 and the lncRNA Hottip/HOTTIP, regulating chromatin modifications that promote the expression of HOXA9, associated with aggressive cancer traits.
- Targeting HOXA9 could serve as a therapeutic strategy to inhibit TWIST1-driven prostate cancer progression, revealing a link between embryonic development and cancer metastasis.
