Publications by authors named "Arul Prakasam"
Article Synopsis
- Researchers identified and characterized a new flavonol compound, opuntiol, from cactus pads using chromatography and various spectroscopy methods.* -
- The structure of opuntiol was determined to be near planar and stabilized by specific hydrogen bonds, as shown through single-crystal X-ray diffraction.* -
- Opuntiol demonstrated significant anti-proliferative effects on KB cancer cells, inducing ROS generation and apoptosis, with an inhibition concentration (IC) value of 30 µM.*
Conformational polymorphs of isobutyl-6-amino-5-cyano-2-methyl-4-phenyl-4H-pyran-3-carboxylate: spectroscopic, structural and DFT approach.
Acta Crystallogr B Struct Sci Cryst Eng Mater
June 2016
The crystal structure of a new crystalline phase, polymorph (II) of isobutyl-6-amino-5-cyano-2-methyl-4-phenyl-4H-pyran-3-carboxylate, was accurately determined by single-crystal X-ray diffraction analysis providing a clean identification of polymorphic forms. Comparison with a known phase, referred to as polymorph (I), reveals the type of supramolecular assembly. Inter- and intramolecular hydrogen-bonding interactions exhibit various supramolecular architectures in crystal packing and these variations confirm well the polymorphism in isobutyl-6-amino-5-cyano-2-methyl-4-phenyl-4H-pyran-3-carboxylate (IAPC) crystal structure.
View Article and Find Full Text PDFCrystal structure of isobutyl 4-(2-chloro-phen-yl)-5-cyano-6-{(E)-[(di-methyl-amino)-methyl-idene]amino}-2-methyl-4H-pyran-3-carboxyl-ate.
Acta Crystallogr E Crystallogr Commun
February 2015
In the title compound, C21H24ClN3O3, the dihedral angle between the pyran ring (r.m.s.
View Article and Find Full Text PDFKnowledge, perception and practice of pharmacovigilance among community pharmacists in South India.
Pharm Pract (Granada)
October 2012
Unlabelled: Pharmacovigilance has not progressed well in India and the concept is still in its infancy. India rates below 1% in pharmacovigilance as against the world rate of 5%.
Objective: The aim of our study was to evaluate the knowledge, perception and practice of pharmacovigilance among registered community pharmacists in Hyderabad, India.