Publications by authors named "Aru Liu"
Aims: In the present study, we aimed to uncover the potential functions of circular RNA (circRNA) pleckstrin and Sec7 domain containing 3 (circ_PSD3) in papillary thyroid carcinoma (PTC) development.
Main Methods: The abundance of circ_PSD3, PSD3 messenger RNA (mRNA), microRNA-637 (miR-637) and hemogen (HEMGN; EDAG-1) mRNA was detected by quantitative real-time polymerase chain reaction (qRT-PCR). Flow cytometry was employed to measure cell cycle progression and cell apoptosis.
Article Synopsis
- The study aims to investigate changes in the expression of the apoptosis-related protein ARTS in lung tissues following acute pulmonary embolism (APE) in rats, focusing on how it affects cell apoptosis.
- Methods included creating a rat model of APE, collecting lung tissue samples at different times, measuring ARTS and related protein levels using techniques like RT-PCR and Western blotting, and identifying apoptotic cells through the TUNEL method.
- Results showed significant increases in ARTS mRNA and protein levels at specific time points after APE, with a notable presence in bronchial and alveolar epithelial cells, alongside a rise in apoptosis levels and a decrease in anti-apoptotic proteins compared to healthy controls.