Publications by authors named "Arturo Puja"
Orphanet J Rare Dis
September 2021
Article Synopsis
- Homozygous familial hypercholesterolemia (HoFH) is a rare and severe condition that is difficult to treat, often requiring both lipid-lowering medications and lipoprotein apheresis (LA) for management.
- A study comparing two groups of HoFH patients treated with lomitapide and LA showed that lomitapide resulted in a greater reduction in LDL-C levels and a possibly lower cardiovascular event rate, despite the fact that treatment goals were not fully met for a large portion of patients in either group.
- The findings suggest that lomitapide may offer better LDL-C control compared to LA, but further research is necessary to determine its impact on overall cardiovascular risk.
