Publications by authors named "Arturo Ota"
Objective: To describe the effect of reoxygenation with 100% O2 as compared to the effect of room air in newborn rat brains after asphyxia.
Methods: Experimental asphyxia (carotid artery ligation followed by hypoxic exposure with 8% O2 for 2 h) was performed on 7-day-old rats. After hypoxia-ischemia the rats were reoxygenated with either 100% O2 (hyperoxia group) or 21% O2 (room air group) for 24 h and then returned to the dam.
Background: Studies showed that propentofylline enhances the action of adenosine and protects hippocampal neuronal damage against transient global cerebral ischaemia. Our study was to investigate the effect of propentofylline on hypoxic-ischaemic brain damage in neonatal rat.
Methods: Seven-day-old Wistar rats were subjected to unilateral common carotid artery ligation and hypoxia in oxygen 8 kPa for two hours at 37 degrees C.
Article Synopsis
- The study aimed to investigate how injection sites affect blood flow patterns in newborn rats using colored microspheres (CMS).
- Open-chest models demonstrated that CMS injected into the right ventricle only entered the lungs, while left ventricle injections resulted in systemic distribution.
- In closed-chest models, most injections showed no significant difference in blood flow between the right and left sides of various organs, indicating that this microsphere technique can effectively measure blood flow distribution in young rats.