Integrative taxonomy of Metarhizium anisopliae species complex, based on phylogenomics combined with morphometrics, metabolomics, and virulence data.

Metarhizium anisopliae (Clavicipitaceae, Hypocreales) is a globally distributed entomopathogenic fungus, which has been largely studied and used in agriculture for its potent entomopathogenicity. Since its taxonomic establishment as a member of Metarhizium, many closely related taxa have been described with highly similar morphology (cryptic species). A holotype specimen of M.

Bioactive Bioxanthracene and Cyclodepsipeptides from the Entomopathogenic Fungus BCC56290.

In the course of our ongoing research targeting the identification of potential biocontrol agents from entomopathogenic fungi (EPF), we explored a solid-state rice fungal extract of BCC56290 derived from infected lepidopteran larvae. Chemical and biological prospections afforded four unprecedentedly reported natural products differentiated into a dimeric naphthopyran bioxanthracene ES-242 derivative () and three cyclodepsipeptides (-) in addition to two known cyclodepsipeptides, cardinalisamides B () and C (). Chemical structures of the isolated compounds were elucidated through comprehensive 1D/2D NMR and HR-ESI-MS data together with comparisons to the reported literature.

Depicting the Chemical Diversity of Bioactive Meroterpenoids Produced by the Largest Organism on Earth.

In this investigation, we explored the diversity of melleolide-type meroterpenoids produced by Armillaria ostoyae, one of the largest and oldest organisms on Earth, using extracts from liquid and solid fermentation media. The study unveiled three unprecedented dimeric bismelleolides and three novel fatty-acid-substituted congeners, along with 11 new and 21 known derivatives. The structures were elucidated by 1D and 2D NMR spectroscopy and HRESI-MS, and ROESY spectral analysis for relative configurations.

Bioprospection of Tenellins Produced by the Entomopathogenic Fungus .

Fungi are known as prolific producers of bioactive secondary metabolites with applications across various fields, including infectious diseases, as well as in biological control. However, some of the well-known species are still underexplored. Our current study evaluated the production of secondary metabolites by the entomopathogenic fungus from Thailand.

Cytotoxic cytochalasans from cultures of the fungus TBRC-BCC 79240.

Fourteen new cytochalasans, brunnesins A-N (1-14), along with eleven known compounds, were isolated from the culture extracts of the insect pathogenic fungus strain TBRC-BCC 79240. The compound structures were established by spectroscopy, X-ray diffraction analysis, and electronic circular dichroism. Compound 4 exhibited antiproliferative activity against all cell lines tested (mammalian), with 50% inhibition concentration (IC) values ranging from 2.

Comprehensive treatise of and three new genera , and on spiders in Cordycipitaceae from Thailand.

Collections of pathogenic fungi found on spiders from Thailand were selected for a detailed taxonomic study. Morphological comparison and phylogenetic analyses of the combined ITS, LSU, , and sequence data indicated that these specimens formed new independent lineages within the Cordycipitaceae, containing two new genera occurring on spiders, i.e.

Is Congeneric with ? Phylogenetic Relationships of spp. (, ) and a New Genus on Scale Insects in Thailand.

During surveys of insect pathogenic fungi (IPF) in Thailand, fungi associated with scale insects and plants were found to represent five new species of the genus in . Their macroscopic features resembled both and . Morphological comparisons with the type and known and species and phylogenetic evidence from a multigene dataset support the appointment of a new species of .

Phylogeny- and morphology-based recognition of new species in the spider-parasitic genus (Hypocreales, Cordycipitaceae) from Thailand.

Thailand is known to be a part of what is called the Indo-Burma biodiversity hotspot, hosting a vast array of organisms across its diverse ecosystems. This is reflected by the increasing number of new species described over time, especially fungi. However, a very few fungal species from the specialized spider-parasitic genus have ever been reported from this region.

Phylogenetic and morphological classification of species on termites from Thailand.

Seven new species occurring on termites are added to - , , , , , and , based on morphological and molecular phylogenetic evidence. possesses orange to reddish-brown immersed perithecia on cylindrical to clavate stromata. , and have pseudo-immersed perithecia while , and all possess superficial perithecia, reminiscent of and .

New species of Ophiocordyceps unilateralis, an ubiquitous pathogen of ants from Thailand.

Ophiocordyceps unilateralis is an ubiquitous pathogen of ants with hidden phylogenetic diversity associated with host specificity. In this study, we describe two new species to this species complex: Ophiocordyceps septa and Ophiocordyceps rami. Both were found on unidentified ants of the genus Camponotus (C.

Phenolic glycosides from the filamentous fungus Acremonium sp. BCC 14080.

New phenolic mono- and digalactopyranosides (1 and 2), their aglycone KS-501a (3), and a new phenolic 4-O-methylglucopyranoside (4) were isolated from the filamentous fungus Acremonium sp. BCC 14080. Structures of these compounds were elucidated by extensive MS and NMR spectroscopic analyses.