Antimicrobial peptide-based strategies to overcome antimicrobial resistance.

Antibiotic resistance has emerged as a global threat, rendering the existing conventional treatment strategies ineffective. In view of this, antimicrobial peptides (AMPs) have proven to be potent alternative therapeutic interventions with a wide range of applications in clinical health. AMPs are small peptides produced naturally as a part of the innate immune responses against a broad range of bacterial, fungal and viral pathogens.

Structural-functional analysis and molecular characterization of arsenate reductase from RSC3 for arsenic biotransformation.

Unlabelled: RSC3 isolated from an industrial pesticide site transformed arsenate into arsenite. The arsenate is transported by membrane-bound phosphate transporter and transformed to arsenite by arsenate reductase (C). RSC3 produced an arsenate reductase enzyme with a maximum activity of 354 U after 72 h of incubation.

Cultivation and conservation of underutilized medicinal and agricultural plants in India.

In the current era, the increased demand of healthy food rich in antioxidants, vitamins and minerals and those having therapeutic value has led to over-exploitation of major agricultural and medicinal plants. This overburden can be reduced by an efficient utilization of underutilized plants with nutritional and medicinal importance. These underutilized plants are neglected or undervalued 'minor' crops having low production and sale.

Role of Polypeptide Inflammatory Biomarkers in the Diagnosis and Monitoring of COVID-19.

The COVID-19 (coronavirus disease 2019) pandemic that took over the world in December 2019 has had everlasting devastating impacts on the lives of people globally. It manifests a huge symptom spectrum ranging from asymptomatic to critically ill patients with an unpredictable outcome. Timely diagnosis and assessment of disease severity is imperative for effective treatment.

Analyzing the Use of Medicinal Herbs During the First Wave and Second Wave of COVID-19.

India has confronted the COVID-19 pandemic in 2020, in the form of first wave and again in first half of 2021 in the form of second wave. To combat the persistent transmission of the coronavirus, Indian Government has started the vaccination in the country since January 2021. The immunity conferred by the vaccine can be more effective with sound immune health.

Computational-approach understanding the structure-function prophecy of Fibrinolytic Protease RFEA1 from RSA1.

Microbial fibrinolytic proteases are therapeutic enzymes responsible to ameliorate thrombosis, a fatal cardiac-disorder which effectuates due to excessive fibrin accumulation in blood vessels. Inadequacies such as low fibrin specificity, lethal after-effects and short life-span of available fibrinolytic enzymes stimulates an intensive hunt for novel, efficient and safe substitutes. Therefore, we herewith suggest a novel and potent fibrinolytic enzyme RFEA1 from RSA1 (MK288105).

Profile of Lymphadenopathy: An Institutional Based Cytomorphological Study.

Introduction: Lymphadenopathy is one of the most common clinical presentations of patients attending the outdoor department of a hospital. Lymph node aspiration is of great value for the diagnosis of lymphadenitis, lymphomas, and metastatic carcinoma.

Materials And Methods: In this study, we have reported the pattern of cytological diagnosis on fine-needle aspiration cytology (FNAC) of lymphadenopathy cases in Jammu region of Jammu and Kashmir state of India.

Anesthesiologists and acute perioperative stress: a cohort study.

Unlabelled: Previous studies have indicated that many anesthesiologists exhibit symptoms of chronic stress. There is a paucity of data, however, regarding the existence of acute stress signs among anesthesiologists. Anesthesiologists from three practice settings (n = 38) were studied while they were anesthetizing 203 patients.