Extended Gastrectomy for T4b Gastric Adenocarcinoma: Single-Surgeon Experience.

Purpose: This study reports single-surgeon experience with extended gastrectomy including en-bloc resection of adjacent organs/structures for T4b stage gastric adenocarcinoma. Time-related changes in patient selection criteria and outcomes were also analyzed.

Methods: All consecutive gastrectomies for adenocarcinoma performed between May 2004 and December 2017 were extracted from prospectively collected database to study surgical and oncologic results.

Characterization of mutations in patients with family history of breast cancer in Armenia.

Breast cancer is one of the most common cancers in women worldwide. The germline mutations of the and genes are the most significant and well characterized genetic risk factors for hereditary breast cancer. Intensive research in the last decades has demonstrated that the incidence of mutations varies widely among different populations.